Weaning children from mechanical ventilation with a computer-driven protocol: a pilot trial

Purpose Duration of weaning from mechanical ventilation is decreased with the use of written protocols in adults. In children, the use of written protocols has not had such an impact. Methods and measurements We conducted a single-center trial to assess the feasibility of conducting a multicenter ra...

Full description

Saved in:
Bibliographic Details
Published in:Intensive care medicine 2013-05, Vol.39 (5), p.919-925
Main Authors: Jouvet, Philippe A., Payen, Valérie, Gauvin, France, Emeriaud, Guillaume, Lacroix, Jacques
Format: Article
Language:English
Subjects:
Adolescent
Anesthesiology
Care and treatment
Child
Child, Preschool
Children
Clinical trials
Critical Care Medicine
Decision Making
Emergency Medicine
Extubation
Female
Health aspects
Hospitals
Humans
Infant
Intensive
Intensive care
Intensive Care Units, Pediatric
Male
Medicine
Medicine & Public Health
Pain Medicine
Patient outcomes
Patients
Pediatric Original
Pediatrics
Pilot Projects
Pneumology/Respiratory System
Proportional Hazards Models
Respiration, Artificial
Statistics, Nonparametric
Therapy, Computer-Assisted
Treatment Outcome
Ventilator weaning
Ventilator Weaning - methods
Ventilators
Weaning
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose Duration of weaning from mechanical ventilation is decreased with the use of written protocols in adults. In children, the use of written protocols has not had such an impact. Methods and measurements We conducted a single-center trial to assess the feasibility of conducting a multicenter randomized clinical trial comparing the duration of weaning from mechanical ventilation in those managed by a computer-driven explicit protocol versus usual care. Mechanically ventilated children aged between 2 and 17 years on pressure support and not receiving inotropes were included. After randomization, children were weaned either by usual care ( n  = 15) that was characterized by no protocolized decisions by attending physicians, or by a computer-driven protocol (Smartcare/PS™, Drager Medical) ( n  = 15). Weaning duration until first extubation was the primary outcome. For comparison, a Mann–Whitney U test was employed ( p  
ISSN:0342-4642
1432-1238
DOI:10.1007/s00134-013-2837-8