Serum Uric Acid Levels are Associated With Atrial Fibrillation in Patients With Ischemic Heart Failure

We evaluated the association between serum uric acid (SUA) and atrial fibrillation (AF) in patients with chronic heart failure (HF). Totally, 363 patients with chronic HF were included in the study. Of all, 78 patients had AF and 285 patients were in normal sinus rhythm. Serum uric acid was signific...

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Bibliographic Details
Published in:Angiology 2013-05, Vol.64 (4), p.300-303
Main Authors: Tekin, Gulacan, Tekin, Yusuf Kenan, Erbay, Ali Rıza, Turhan, Hasan, Yetkin, Ertan
Format: Article
Language:English
Subjects:
Aged
Atrial Fibrillation - blood
Atrial Fibrillation - diagnosis
Atrial Fibrillation - etiology
Atrial Fibrillation - physiopathology
Biomarkers - blood
Chronic Disease
Female
Heart Atria - diagnostic imaging
Heart Failure - blood
Heart Failure - diagnosis
Heart Failure - etiology
Heart Failure - physiopathology
Humans
Logistic Models
Male
Middle Aged
Myocardial Ischemia - complications
Retrospective Studies
Risk Factors
Stroke Volume
Ultrasonography
Up-Regulation
Uric Acid - blood
Ventricular Function, Left
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Summary:We evaluated the association between serum uric acid (SUA) and atrial fibrillation (AF) in patients with chronic heart failure (HF). Totally, 363 patients with chronic HF were included in the study. Of all, 78 patients had AF and 285 patients were in normal sinus rhythm. Serum uric acid was significantly increased in patients with AF compared with patients in normal sinus rhythm (P < .05). Comparing patients with AF and normal sinus rhythm, we found that age was significantly higher in patients group with AF. Echocardiographic parameters including ejection fraction, left atrial diameter, left ventricle end-diastolic diameter, and left ventricle end-diastolic volume were also significantly higher in patients with AF compared with patients in normal sinus rhythm. We have shown that patients with AF have significantly higher SUA and this was independently associated with AF in patients with ischemic HF.
ISSN:0003-3197
1940-1574
DOI:10.1177/0003319712448247