The impact of metabolic syndrome and endothelial dysfunction on exercise‐induced cardiovascular changes

Objective: There is limited information regarding the synergistic or additive effects of metabolic syndrome (MS) and endothelial dysfunction (ED) on cardiovascular disease (CVD). Altered cardiovascular responses to exercise have been shown to predict future cardiovascular events as well as assess au...

Full description

Saved in:
Bibliographic Details
Published in:Obesity (Silver Spring, Md.) Md.), 2013-01, Vol.21 (1), p.E143-E148
Main Authors: Rossi, Amanda M., Davies, Elaine, Lavoie, Kim L., Arsenault, André, Gordon, Jennifer L., Meloche, Bernard, Bacon, Simon L.
Format: Article
Language:English
Subjects:
Adult
Aged
Blood Pressure
Brachial Artery - physiopathology
Cardiovascular Diseases - metabolism
Cardiovascular Diseases - physiopathology
Endothelium, Vascular - physiopathology
Exercise - physiology
Exercise Test
Female
Heart Rate
Humans
Male
Metabolic Syndrome - physiopathology
Middle Aged
Parasympathetic Nervous System - physiopathology
Vasodilation
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective: There is limited information regarding the synergistic or additive effects of metabolic syndrome (MS) and endothelial dysfunction (ED) on cardiovascular disease (CVD). Altered cardiovascular responses to exercise have been shown to predict future cardiovascular events as well as assess autonomic function. The present study evaluated the impact of MS and brachial artery reactivity (a proxy of ED) on peak exercise‐induced cardiovascular changes. Design and Methods: Individuals (n = 303) undergoing a standard nuclear medicine exercise stress test were assessed for MS. Participants underwent a Forearm Hyperaemic Reactivity test and were considered to have dysfunctional reactivity if their rate of uptake ratio (RUR) was
ISSN:1930-7381
1930-739X
DOI:10.1002/oby.20258