Invited commentary: missing doses in the life span study of Japanese atomic bomb survivors

The Life Span Study is a long-term epidemiologic cohort study of survivors of the atomic bombs dropped on Hiroshima and Nagasaki, Japan. In this issue of the Journal, Richardson et al. (Am J Epidemiol. 2013;177(6):562-568) suggest that those who died in the earliest years of follow-up were more like...

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Bibliographic Details
Published in:American journal of epidemiology 2013-03, Vol.177 (6), p.569-573
Main Authors: Ozasa, K, Grant, E J, Cullings, H M, Shore, R E
Format: Article
Language:English
Subjects:
Female
Humans
Male
Neoplasms, Radiation-Induced - mortality
Nuclear Weapons
Radiation Dosage
Survivors
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Summary:The Life Span Study is a long-term epidemiologic cohort study of survivors of the atomic bombs dropped on Hiroshima and Nagasaki, Japan. In this issue of the Journal, Richardson et al. (Am J Epidemiol. 2013;177(6):562-568) suggest that those who died in the earliest years of follow-up were more likely to have a missing dose of radiation exposure assigned, leading to a bias in the radiation risk estimates. We show that nearly all members of the cohort had shielding information recorded before the beginning of follow-up and that much of the alleged bias that Richardson et al. describe simply reflects the geographic distribution of shielding conditions for which reliable dosimetry was impossible.
ISSN:0002-9262
1476-6256
DOI:10.1093/aje/kws474