The association between some endocrine disruptors in human plasma and the occurrence of congenital hypothyroidism

Highlights ► t-OP and PA have a statistical association with the congenital hypothyroidism. ► The genistein levels were significantly higher in the normal infants than patients. ► The genistein could affect the improvement of congenital hypothyroidism. ► t-OP was a positively weak correlation betwee...

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Bibliographic Details
Published in:Environmental toxicology and pharmacology 2013-03, Vol.35 (2), p.278-283
Main Authors: Jung, Hyunju, Hong, Yonghee, Lee, Donghwan, Pang, Kijung, Kim, Yunje
Format: Article
Language:English
Subjects:
Association
Benzhydryl Compounds - blood
Child, Preschool
Congenital hypothyroidism
Congenital Hypothyroidism - blood
Diethylhexyl Phthalate - analogs & derivatives
Diethylhexyl Phthalate - blood
Emergency
Endocrine disruptors
Endocrine Disruptors - blood
Female
Gas Chromatography-Mass Spectrometry - methods
GC–MS
Humans
Infant
Infant, Newborn
Isoflavones
Isoflavones - blood
Mothers
Phenols - blood
Phthalic Acids - blood
Reference Values
Reproducibility of Results
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Summary:Highlights ► t-OP and PA have a statistical association with the congenital hypothyroidism. ► The genistein levels were significantly higher in the normal infants than patients. ► The genistein could affect the improvement of congenital hypothyroidism. ► t-OP was a positively weak correlation between mother and infant.
ISSN:1382-6689
1872-7077
DOI:10.1016/j.etap.2013.01.002