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Ogilvie's syndrome in severe dengue

Most infections are asymptomatic, but a wide variety of clinical manifestations, from mild febrile illness to severe and fatal disease, can occur.1 Dengue virus infection presents with or without warning signs, and patients recover without major complications or develop severe dengue.2 Young age, fe...

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Bibliographic Details
Published in:The Lancet (British edition) 2013-02, Vol.381 (9867), p.698-698
Main Authors: Anam, Ahmad Mursel, MBBS, Rabbani, Raihan, MD
Format: Article
Language:English
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Summary:Most infections are asymptomatic, but a wide variety of clinical manifestations, from mild febrile illness to severe and fatal disease, can occur.1 Dengue virus infection presents with or without warning signs, and patients recover without major complications or develop severe dengue.2 Young age, female sex, high body-mass index, virus strain, and genetic variants have been identified as risk factors1 for severe dengue. Early convalescent stage IgM concentrations are substantially lower in secondary than in primary infections and might sometimes be undetectable.2 Ogilvie's syndrome is a clinical condition with the symptoms, signs, and radiographic appearance of acute large bowel obstruction, without evidence of a mechanical cause.3,4 Infectious, metabolic, pharmacological, or traumatic factors can alter the autonomic regulation of colonic function, causing colonic atony and pseudo-obstruction.3 Nausea, vomiting, abdominal distension, and pain are common symptoms at presentation.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(12)62031-5