MEDIUM-GRADE ASTROCYTOMA IN A COUGAR (PUMA CONCOLOR)

A 17-year-old, male castrated cougar (Puma concolor) was presented minimally responsive and severely depressed, with bilateral mydriasis and absent pupillary light response. On gross examination of the brain, there was a tan-to-gray, invasive mass with a central cavitation on the ventral aspect in t...

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Bibliographic Details
Published in:Journal of zoo and wildlife medicine 2012-12, Vol.43 (4), p.956-960
Main Authors: Kondo, Hirotaka, Leone, Angelique M, Erlacher-Reid, Claire, Gary, Joy, Kiupel, Matti, Farina, Lisa L, Abbott, Jeffrey R
Format: Article
Language:English
Subjects:
Animals
Antibodies
Astrocytoma
Astrocytoma - pathology
Astrocytoma - veterinary
Brain Neoplasms - pathology
Brain Neoplasms - veterinary
BRIEF COMMUNICATIONS
Central nervous system
cougar
Glioma
Male
Neoplasia
Neurons
Pathology
Puma
Puma concolor
Tumors
Zoos
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Summary:A 17-year-old, male castrated cougar (Puma concolor) was presented minimally responsive and severely depressed, with bilateral mydriasis and absent pupillary light response. On gross examination of the brain, there was a tan-to-gray, invasive mass with a central cavitation on the ventral aspect in the left cerebral hemisphere, rostral to the caudate nucleus. On histopathologic examination, the mass was composed of sheets of medium-sized, round-to-polygonal cells that were multifocally separated by islands of neuropil. Approximately 80% of the neoplastic cells showed strong cytoplasmic labeling for glial fibrillary acidic protein. These findings were consistent with a medium-grade astrocytoma. To the authors' knowledge, neoplastic disease of the central nervous system has not been previously reported in cougars.
ISSN:1042-7260
1937-2825
DOI:10.1638/2012-0106R1.1