Mitochondrial metabolism in aging: Effect of dietary interventions

Highlights ► Mitochondrial energy metabolism is central toward aging. ► We focus on the relationship between mitochondrial redox state, aging and dietary interventions. ► Which modifications induced by diet are central in aging remains to be fully understood. ► Diets used for laboratory animals are...

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Bibliographic Details
Published in:Ageing research reviews 2013-01, Vol.12 (1), p.22-28
Main Authors: Cerqueira, Fernanda M, Kowaltowski, Alicia J
Format: Article
Language:English
Subjects:
Aging - metabolism
Animals
Caloric Restriction
Diet
Energy Metabolism - physiology
Humans
Internal Medicine
Longevity
Mitochondria - metabolism
Neurology
Oxidants
Reactive Nitrogen Species - metabolism
Reactive Nitrogen Species - physiology
Reactive Oxygen Species - metabolism
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Summary:Highlights ► Mitochondrial energy metabolism is central toward aging. ► We focus on the relationship between mitochondrial redox state, aging and dietary interventions. ► Which modifications induced by diet are central in aging remains to be fully understood. ► Diets used for laboratory animals are variable, and of difficult comparison with humans. ► Mechanistically understanding effects of diets will help translate into positive human effects.
ISSN:1568-1637
1872-9649
DOI:10.1016/j.arr.2012.03.009