Usefulness of presepsin in the diagnosis of sepsis in a multicenter prospective study

Abstract The clinical usefulness of presepsin for discriminating between bacterial and nonbacterial infections (including systemic inflammatory response syndrome) was studied and compared with procalcitonin (PCT) and interleukin-6 (IL-6) in a multicenter prospective study. Suspected sepsis patients...

Full description

Saved in:
Bibliographic Details
Published in:Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2012, Vol.18 (6), p.891-897
Main Authors: Endo, Shigeatsu, Suzuki, Yasushi, Takahashi, Gaku, Shozushima, Tatsuyori, Ishikura, Hiroyasu, Murai, Akira, Nishida, Takeshi, Irie, Yuhei, Miura, Masanao, Iguchi, Hironobu, Fukui, Yasuo, Tanaka, Kimiaki, Nojima, Tsuyoshi, Okamura, Yoshikazu
Format: Article
Language:eng
Subjects:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract The clinical usefulness of presepsin for discriminating between bacterial and nonbacterial infections (including systemic inflammatory response syndrome) was studied and compared with procalcitonin (PCT) and interleukin-6 (IL-6) in a multicenter prospective study. Suspected sepsis patients ( n = 207) were enrolled into the study. Presepsin levels in patients with systemic bacterial infection and localized bacterial infection were significantly higher than in those with nonbacterial infections. In addition, presepsin, PCT, and IL-6 levels in patients with bacterial infectious disease were significantly higher than in those with nonbacterial infectious disease ( P < 0.0001, P < 0.0001, and P  
ISSN:1341-321X
1437-7780