Symptoms in advanced pancreatic cancer are of importance for energy intake

Purpose Cancer cachexia and low energy intake (EI) probably contribute to weight loss in advanced pancreatic cancer (PC). However, little is known about the actual EI in this disease. Aims were to assess EI, weight loss and symptoms during the disease course and investigate associations between symp...

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Bibliographic Details
Published in:Supportive care in cancer 2013-01, Vol.21 (1), p.219-227
Main Authors: Bye, Asta, Jordhøy, Marit S., Skjegstad, Grete, Ledsaak, Oddlaug, Iversen, Per Ole, Hjermstad, Marianne Jensen
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Cachexia - etiology
Cachexia - prevention & control
Diet
Energy Intake
Female
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Norway
Nursing
Nursing Research
Oncology
Original Article
Pain Medicine
Pancreatic cancer
Pancreatic Neoplasms - complications
Prospective Studies
Rehabilitation Medicine
Survival Analysis
Symptom Assessment
Weight
Weight Loss
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Summary:Purpose Cancer cachexia and low energy intake (EI) probably contribute to weight loss in advanced pancreatic cancer (PC). However, little is known about the actual EI in this disease. Aims were to assess EI, weight loss and symptoms during the disease course and investigate associations between symptoms and EI. Methods Thirty-nine patients (21 males) with advanced PC were consecutively included and followed every 4 weeks until the end of life. A 24-h dietary recall was used to assess EI. The Edmonton Symptom Assessment System (ESAS) and the PC-specific health-related quality of life questionnaire (QLQ-PAN26) were used for symptom assessment. Results Median age was 62 years (48–88), WHO performance status 1 (0–2) and survival 5 months (1–25). Seventeen (44 %) patients had unresectable cancer, 16 (41 %) metastatic and six (15 %) recurrent disease. Upon inclusion, 37 (95 %) reported weight loss (median 4.0 kg per month). During follow-up, median weight loss per month was
ISSN:0941-4355
1433-7339
DOI:10.1007/s00520-012-1514-8