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Intralesional Cidofovir in the Treatment of Cutaneous Warts in a Renal Transplant Patient
Background: Cutaneous warts are often recalcitrant to conventional therapy in immunocompromised patients. Cidofovir is a potent antiviral agent shown to have a broad spectrum of action against DNA virus, including human papillomavirus. Objective: To determine the efficacy of intralesional cidofovir...
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| Published in: | Journal of cutaneous medicine and surgery 2012-11, Vol.16 (6), p.462-464 |
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| Format: | Article |
| Language: | English |
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| container_end_page | 464 |
| container_issue | 6 |
| container_start_page | 462 |
| container_title | Journal of cutaneous medicine and surgery |
| container_volume | 16 |
| creator | Blouin, Marie-Michèle Cloutier, Richard Noël, Réal |
| description | Background:
Cutaneous warts are often recalcitrant to conventional therapy in immunocompromised patients. Cidofovir is a potent antiviral agent shown to have a broad spectrum of action against DNA virus, including human papillomavirus.
Objective:
To determine the efficacy of intralesional cidofovir in the treatment of florid warts in an immunocompromised renal transplant patient.
Method:
The patient received seven injections of intralesional cidofovir at 4 week intervals in his numerous palmar warts.
Conclusion:
Based on our results, intralesional cidofovir is a promising therapeutic modality in the treatment of cutaneous warts in the renal transplant population.
Contexte:
Les verrues cutanées se montrent souvent réfractaires au traitement habituel chez les immunodéficients. Le cidofovir est un antiviral puissant, doté d'un large spectre d'action contre les virus à ADN, y compris contre le papillomavirus humain.
Objectif:
L'étude visait à déterminer l'efficacité du cidofovir intralésionnel dans le traitement de verrues florides chez un patient immunodéprimé, ayant subi une transplantation rénale.
Méthode:
Le patient a reçu sept injections de cidofovir intralésionnel, à 4 semaines d'intervalle, dans les nombreuses verrues palmaires.
Conclusion:
D'après les résultats obtenus, le cidofovir intralésionnel serait porteur d'avenir dans le traitement des verrues cutanées chez les patients ayant subi une transplantation rénale. |
| doi_str_mv | 10.1177/120347541201600622 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1171882721</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_120347541201600622</sage_id><sourcerecordid>1171882721</sourcerecordid><originalsourceid>FETCH-LOGICAL-c401t-837c44326498d355bdb30d3d9e6ba1c61c412a56db0bb0104837196b6698d4e73</originalsourceid><addsrcrecordid>eNp10MtKxDAUBuAgijNeXsCFFERwUycnSZN2KcXLwIAiI-KqpG2qGXoZk1Tw7U3peEFxlSy-_-TkR-gI8DmAEDMgmDIRMX8Cx5gTsoWmwCEKBeBk2989CAcxQXvWrjDGABHbRRNCgSUEJ1P0NG-dkbWyumtlHaS67KruTZtAt4F7UcHSKOka1bqgq4K0d7JVXW-DR2mcHYwM7tUQXBrZ2nUtPbyTTvvAAdqpZG3V4ebcRw9Xl8v0JlzcXs_Ti0VYMAwujKkoGKOEsyQuaRTlZU5xSctE8VxCwaHw_5MRL3Oc5xgw8wFIeM6590wJuo_Oxrlr0732yrqs0bZQdT2umvmqII6JIODpyS-66nrj1_eKCMxFQgnzioyqMJ21RlXZ2uhGmvcM8DBNZH-L96Hjzeg-b1T5Ffls2oPTDZC2kHXl-yq0_XZcUELiYdBsdFY-qx_7_f_0B2r8lYI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1270679324</pqid></control><display><type>article</type><title>Intralesional Cidofovir in the Treatment of Cutaneous Warts in a Renal Transplant Patient</title><source>SAGE</source><creator>Blouin, Marie-Michèle ; Cloutier, Richard ; Noël, Réal</creator><creatorcontrib>Blouin, Marie-Michèle ; Cloutier, Richard ; Noël, Réal</creatorcontrib><description>Background:
Cutaneous warts are often recalcitrant to conventional therapy in immunocompromised patients. Cidofovir is a potent antiviral agent shown to have a broad spectrum of action against DNA virus, including human papillomavirus.
Objective:
To determine the efficacy of intralesional cidofovir in the treatment of florid warts in an immunocompromised renal transplant patient.
Method:
The patient received seven injections of intralesional cidofovir at 4 week intervals in his numerous palmar warts.
Conclusion:
Based on our results, intralesional cidofovir is a promising therapeutic modality in the treatment of cutaneous warts in the renal transplant population.
Contexte:
Les verrues cutanées se montrent souvent réfractaires au traitement habituel chez les immunodéficients. Le cidofovir est un antiviral puissant, doté d'un large spectre d'action contre les virus à ADN, y compris contre le papillomavirus humain.
Objectif:
L'étude visait à déterminer l'efficacité du cidofovir intralésionnel dans le traitement de verrues florides chez un patient immunodéprimé, ayant subi une transplantation rénale.
Méthode:
Le patient a reçu sept injections de cidofovir intralésionnel, à 4 semaines d'intervalle, dans les nombreuses verrues palmaires.
Conclusion:
D'après les résultats obtenus, le cidofovir intralésionnel serait porteur d'avenir dans le traitement des verrues cutanées chez les patients ayant subi une transplantation rénale.</description><identifier>ISSN: 1203-4754</identifier><identifier>EISSN: 1615-7109</identifier><identifier>DOI: 10.1177/120347541201600622</identifier><identifier>PMID: 23149209</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Adult ; Antiviral Agents - administration & dosage ; Antiviral Agents - therapeutic use ; Biological and medical sciences ; Cytosine - administration & dosage ; Cytosine - analogs & derivatives ; Cytosine - therapeutic use ; Dermatology ; Hand Dermatoses - drug therapy ; Hand Dermatoses - virology ; Human viral diseases ; Humans ; Immunocompromised Host ; Infectious diseases ; Injections, Intralesional ; Kidney Transplantation - immunology ; Male ; Medical research ; Medical sciences ; Medical treatment ; Organophosphonates - administration & dosage ; Organophosphonates - therapeutic use ; Patients ; Viral diseases ; Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye ; Warts ; Warts - drug therapy ; Warts - virology ; Young Adult</subject><ispartof>Journal of cutaneous medicine and surgery, 2012-11, Vol.16 (6), p.462-464</ispartof><rights>2012 Canadian Dermatology Association</rights><rights>2014 INIST-CNRS</rights><rights>Copyright Decker Periodicals, Inc. Nov/Dec 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c401t-837c44326498d355bdb30d3d9e6ba1c61c412a56db0bb0104837196b6698d4e73</citedby><cites>FETCH-LOGICAL-c401t-837c44326498d355bdb30d3d9e6ba1c61c412a56db0bb0104837196b6698d4e73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26732282$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23149209$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Blouin, Marie-Michèle</creatorcontrib><creatorcontrib>Cloutier, Richard</creatorcontrib><creatorcontrib>Noël, Réal</creatorcontrib><title>Intralesional Cidofovir in the Treatment of Cutaneous Warts in a Renal Transplant Patient</title><title>Journal of cutaneous medicine and surgery</title><addtitle>J Cutan Med Surg</addtitle><description>Background:
Cutaneous warts are often recalcitrant to conventional therapy in immunocompromised patients. Cidofovir is a potent antiviral agent shown to have a broad spectrum of action against DNA virus, including human papillomavirus.
Objective:
To determine the efficacy of intralesional cidofovir in the treatment of florid warts in an immunocompromised renal transplant patient.
Method:
The patient received seven injections of intralesional cidofovir at 4 week intervals in his numerous palmar warts.
Conclusion:
Based on our results, intralesional cidofovir is a promising therapeutic modality in the treatment of cutaneous warts in the renal transplant population.
Contexte:
Les verrues cutanées se montrent souvent réfractaires au traitement habituel chez les immunodéficients. Le cidofovir est un antiviral puissant, doté d'un large spectre d'action contre les virus à ADN, y compris contre le papillomavirus humain.
Objectif:
L'étude visait à déterminer l'efficacité du cidofovir intralésionnel dans le traitement de verrues florides chez un patient immunodéprimé, ayant subi une transplantation rénale.
Méthode:
Le patient a reçu sept injections de cidofovir intralésionnel, à 4 semaines d'intervalle, dans les nombreuses verrues palmaires.
Conclusion:
D'après les résultats obtenus, le cidofovir intralésionnel serait porteur d'avenir dans le traitement des verrues cutanées chez les patients ayant subi une transplantation rénale.</description><subject>Adult</subject><subject>Antiviral Agents - administration & dosage</subject><subject>Antiviral Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Cytosine - administration & dosage</subject><subject>Cytosine - analogs & derivatives</subject><subject>Cytosine - therapeutic use</subject><subject>Dermatology</subject><subject>Hand Dermatoses - drug therapy</subject><subject>Hand Dermatoses - virology</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunocompromised Host</subject><subject>Infectious diseases</subject><subject>Injections, Intralesional</subject><subject>Kidney Transplantation - immunology</subject><subject>Male</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Medical treatment</subject><subject>Organophosphonates - administration & dosage</subject><subject>Organophosphonates - therapeutic use</subject><subject>Patients</subject><subject>Viral diseases</subject><subject>Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</subject><subject>Warts</subject><subject>Warts - drug therapy</subject><subject>Warts - virology</subject><subject>Young Adult</subject><issn>1203-4754</issn><issn>1615-7109</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNp10MtKxDAUBuAgijNeXsCFFERwUycnSZN2KcXLwIAiI-KqpG2qGXoZk1Tw7U3peEFxlSy-_-TkR-gI8DmAEDMgmDIRMX8Cx5gTsoWmwCEKBeBk2989CAcxQXvWrjDGABHbRRNCgSUEJ1P0NG-dkbWyumtlHaS67KruTZtAt4F7UcHSKOka1bqgq4K0d7JVXW-DR2mcHYwM7tUQXBrZ2nUtPbyTTvvAAdqpZG3V4ebcRw9Xl8v0JlzcXs_Ti0VYMAwujKkoGKOEsyQuaRTlZU5xSctE8VxCwaHw_5MRL3Oc5xgw8wFIeM6590wJuo_Oxrlr0732yrqs0bZQdT2umvmqII6JIODpyS-66nrj1_eKCMxFQgnzioyqMJ21RlXZ2uhGmvcM8DBNZH-L96Hjzeg-b1T5Ffls2oPTDZC2kHXl-yq0_XZcUELiYdBsdFY-qx_7_f_0B2r8lYI</recordid><startdate>20121101</startdate><enddate>20121101</enddate><creator>Blouin, Marie-Michèle</creator><creator>Cloutier, Richard</creator><creator>Noël, Réal</creator><general>SAGE Publications</general><general>Decker</general><general>SAGE PUBLICATIONS, INC</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20121101</creationdate><title>Intralesional Cidofovir in the Treatment of Cutaneous Warts in a Renal Transplant Patient</title><author>Blouin, Marie-Michèle ; Cloutier, Richard ; Noël, Réal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c401t-837c44326498d355bdb30d3d9e6ba1c61c412a56db0bb0104837196b6698d4e73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Antiviral Agents - administration & dosage</topic><topic>Antiviral Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Cytosine - administration & dosage</topic><topic>Cytosine - analogs & derivatives</topic><topic>Cytosine - therapeutic use</topic><topic>Dermatology</topic><topic>Hand Dermatoses - drug therapy</topic><topic>Hand Dermatoses - virology</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunocompromised Host</topic><topic>Infectious diseases</topic><topic>Injections, Intralesional</topic><topic>Kidney Transplantation - immunology</topic><topic>Male</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Medical treatment</topic><topic>Organophosphonates - administration & dosage</topic><topic>Organophosphonates - therapeutic use</topic><topic>Patients</topic><topic>Viral diseases</topic><topic>Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</topic><topic>Warts</topic><topic>Warts - drug therapy</topic><topic>Warts - virology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Blouin, Marie-Michèle</creatorcontrib><creatorcontrib>Cloutier, Richard</creatorcontrib><creatorcontrib>Noël, Réal</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cutaneous medicine and surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Blouin, Marie-Michèle</au><au>Cloutier, Richard</au><au>Noël, Réal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intralesional Cidofovir in the Treatment of Cutaneous Warts in a Renal Transplant Patient</atitle><jtitle>Journal of cutaneous medicine and surgery</jtitle><addtitle>J Cutan Med Surg</addtitle><date>2012-11-01</date><risdate>2012</risdate><volume>16</volume><issue>6</issue><spage>462</spage><epage>464</epage><pages>462-464</pages><issn>1203-4754</issn><eissn>1615-7109</eissn><notes>ObjectType-Case Study-2</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-4</notes><notes>content type line 23</notes><notes>ObjectType-Report-1</notes><notes>ObjectType-Article-3</notes><abstract>Background:
Cutaneous warts are often recalcitrant to conventional therapy in immunocompromised patients. Cidofovir is a potent antiviral agent shown to have a broad spectrum of action against DNA virus, including human papillomavirus.
Objective:
To determine the efficacy of intralesional cidofovir in the treatment of florid warts in an immunocompromised renal transplant patient.
Method:
The patient received seven injections of intralesional cidofovir at 4 week intervals in his numerous palmar warts.
Conclusion:
Based on our results, intralesional cidofovir is a promising therapeutic modality in the treatment of cutaneous warts in the renal transplant population.
Contexte:
Les verrues cutanées se montrent souvent réfractaires au traitement habituel chez les immunodéficients. Le cidofovir est un antiviral puissant, doté d'un large spectre d'action contre les virus à ADN, y compris contre le papillomavirus humain.
Objectif:
L'étude visait à déterminer l'efficacité du cidofovir intralésionnel dans le traitement de verrues florides chez un patient immunodéprimé, ayant subi une transplantation rénale.
Méthode:
Le patient a reçu sept injections de cidofovir intralésionnel, à 4 semaines d'intervalle, dans les nombreuses verrues palmaires.
Conclusion:
D'après les résultats obtenus, le cidofovir intralésionnel serait porteur d'avenir dans le traitement des verrues cutanées chez les patients ayant subi une transplantation rénale.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>23149209</pmid><doi>10.1177/120347541201600622</doi><tpages>3</tpages></addata></record> |
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| ispartof | Journal of cutaneous medicine and surgery, 2012-11, Vol.16 (6), p.462-464 |
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| language | eng |
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| source | SAGE |
| subjects | Adult Antiviral Agents - administration & dosage Antiviral Agents - therapeutic use Biological and medical sciences Cytosine - administration & dosage Cytosine - analogs & derivatives Cytosine - therapeutic use Dermatology Hand Dermatoses - drug therapy Hand Dermatoses - virology Human viral diseases Humans Immunocompromised Host Infectious diseases Injections, Intralesional Kidney Transplantation - immunology Male Medical research Medical sciences Medical treatment Organophosphonates - administration & dosage Organophosphonates - therapeutic use Patients Viral diseases Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye Warts Warts - drug therapy Warts - virology Young Adult |
| title | Intralesional Cidofovir in the Treatment of Cutaneous Warts in a Renal Transplant Patient |
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