Resection with total caudate lobectomy confers survival benefit in hilar cholangiocarcinoma of Bismuth type III and IV

Abstract Purpose To identify prognostic predictors for overall survival of patients with hilar cholangiocarcinoma of Bismuth type III and IV (HCBT34), and to determine survival benefit and safety of total caudate lobectomy (TCL) in a Chinese centre. Methods From January 2001 to December 2010, 171 pa...

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Published in:	European journal of surgical oncology 2012-12, Vol.38 (12), p.1197-1203
Main Authors:	Cheng, Q.-B, Yi, B, Wang, J.-H, Jiang, X.-Q, Luo, X.-J, Liu, C, Ran, R.-Z, Yan, P.-N, Zhang, B.-H
Format:	Article
Language:	eng
Subjects:	Adult Aged Bile Duct Neoplasms - diagnosis Bile Duct Neoplasms - mortality Bile Duct Neoplasms - surgery Bile Ducts, Intrahepatic China - epidemiology Cholangiocarcinoma Cholangiocarcinoma - diagnosis Cholangiocarcinoma - mortality Cholangiocarcinoma - surgery Female Follow-Up Studies Hematology, Oncology and Palliative Medicine Hepatectomy Hepatectomy - methods Humans Male Middle Aged Neoplasm Staging Prognosis Proportional Hazards Models Retrospective Studies Risk Factors Surgery Survival Rate - trends Treatment Outcome
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Summary:	Abstract Purpose To identify prognostic predictors for overall survival of patients with hilar cholangiocarcinoma of Bismuth type III and IV (HCBT34), and to determine survival benefit and safety of total caudate lobectomy (TCL) in a Chinese centre. Methods From January 2001 to December 2010, 171 patients with the diagnosis of HCBT34, who underwent a potentially curative resection, were included in this study. Cox proportional hazards regression models were used to determine the association between possible prognostic variables and survival time. Curative resectability rate, morbidity and mortality were investigated also. Results Resection with TCL was significantly associated with more opportunity to achieve curative resection ( p
ISSN:	0748-7983 1532-2157