Web-based digital gene expression atlases for the mouse

Over the past 15 years the publicly available mouse gene expression data determined by in situ hybridization have dramatically increased in scope and spatiotemporal resolution. As a consequence of resources and tools available in the post-genomic era, full transcriptomes in the mouse brain and in th...

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Bibliographic Details
Published in:Mammalian genome 2012-10, Vol.23 (9-10), p.525-538
Main Authors: Geffers, Lars, Herrmann, Bernhard, Eichele, Gregor
Format: Article
Language:English
Subjects:
Animal Genetics and Genomics
Animals
Atlases as Topic
Biomedical and Life Sciences
brain
Cell Biology
Gene Expression
Human Genetics
in situ hybridization
Indexing in process
Internet
Life Sciences
mice
Mice - genetics
transcriptome
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Summary:Over the past 15 years the publicly available mouse gene expression data determined by in situ hybridization have dramatically increased in scope and spatiotemporal resolution. As a consequence of resources and tools available in the post-genomic era, full transcriptomes in the mouse brain and in the mouse embryo can be studied. Here we introduce and discuss seven current databases (MAMEP, EMBRYS, GenePaint, EURExpress, EuReGene, BGEM, and GENSAT) that grant access to large collections of expression data in mouse. We review the experimental focus, coverage, data assessment, and annotation for each of these databases and the implementation of analytic tools and links to other relevant databases. We provide a user-oriented summary of how to interrogate each database.
ISSN:0938-8990
1432-1777
DOI:10.1007/s00335-012-9413-3