Recurrent non-small cell lung cancer: evaluation of CT-guided radiofrequency ablation as salvage therapy

Background Radiofrequency ablation (RFA) is a potential application as a salvage tool after failure of surgery, chemotherapy, or radiotherapy of non-small cell lung cancer (NSCLC). Although several studies have evaluated the use of RFA in primary NSCLC, there is little literature on its potential ap...

Full description

Saved in:
Bibliographic Details
Published in:Acta radiologica (1987) 2012-10, Vol.53 (8), p.893-899
Main Authors: Schoellnast, Helmut, Deodhar, Ajita, Hsu, Meier, Moskowitz, Chaya, Nehmeh, Sadek A, Thornton, Raymond H, Sofocleous, Constantinos T, Alago, William, Downey, Robert J, Azzoli, Christopher G, Rosenzweig, Kenneth E, Solomon, Stephen B
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
Carcinoma, Non-Small-Cell Lung - diagnostic imaging
Carcinoma, Non-Small-Cell Lung - mortality
Carcinoma, Non-Small-Cell Lung - surgery
Catheter Ablation
Disease Progression
Disease-Free Survival
Female
Follow-Up Studies
Humans
Investigative techniques, diagnostic techniques (general aspects)
Kaplan-Meier Estimate
Length of Stay
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - mortality
Lung Neoplasms - surgery
Male
Medical sciences
Middle Aged
Neoplasm Recurrence, Local - diagnostic imaging
Neoplasm Recurrence, Local - mortality
Neoplasm Recurrence, Local - surgery
Pneumology
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Retrospective Studies
Surgery, Computer-Assisted
Survival Rate
Tomography, X-Ray Computed
Treatment Outcome
Tumors of the respiratory system and mediastinum
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Radiofrequency ablation (RFA) is a potential application as a salvage tool after failure of surgery, chemotherapy, or radiotherapy of non-small cell lung cancer (NSCLC). Although several studies have evaluated the use of RFA in primary NSCLC, there is little literature on its potential application as a salvage tool. Purpose To evaluate CT-guided RFA employed as a salvage therapy for pulmonary recurrences of NSCLC after prior treatment with chemotherapy, radiation therapy, and/or surgery. Material and Methods A retrospective computer database search yielded 33 patients with biopsy proven primary NSCLC who underwent CT-guided RFA of 39 recurrent tumors following surgery, chemotherapy, and/or radiotherapy. Follow-up imaging was performed with CT and PET-CT. The endpoints of interest were progression-free survival (PFS) and time to local progression (TTLP). PFS and TTLP were compared by lesion size (
ISSN:0284-1851
1600-0455
DOI:10.1258/ar.2012.110333