Ti-Ge binary alloy system developed as potential dental materials

As‐cast Ti–xGe (x = 2, 5, 10, 20 wt %) binary alloys were produced in this work, and various experiments were carried out to investigate the microstructure, mechanical properties, in vitro electrochemical and immersion corrosion behaviors as well as cytotoxicity with as‐cast pure Ti as control, aimi...

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Bibliographic Details
Published in:Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2012-11, Vol.100B (8), p.2239-2250
Main Authors: Lin, Wen-Jiao, Wang, Ben-Li, Qiu, Ke-Jin, Zhou, Fei-Yu, Li, Li, Lin, Jun-Pin, Wang, Yan-Bo, Zheng, Yu-Feng
Format: Article
Language:English
Subjects:
Applied sciences
Biological and medical sciences
Cell Line, Tumor
Corrosion
cytotoxicity
Dental Alloys - chemistry
Exact sciences and technology
Germanium - chemistry
Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics
Humans
Lactic Acid - chemistry
Materials Testing
Maxillofacial surgery. Dental surgery. Orthodontics
mechanical properties
Medical sciences
Metals. Metallurgy
microstructure
Saliva - chemistry
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Technology. Biomaterials. Equipments
Ti-xGe alloys
Titanium - chemistry
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Summary:As‐cast Ti–xGe (x = 2, 5, 10, 20 wt %) binary alloys were produced in this work, and various experiments were carried out to investigate the microstructure, mechanical properties, in vitro electrochemical and immersion corrosion behaviors as well as cytotoxicity with as‐cast pure Ti as control, aiming to study the feasibility of Ti–xGe alloy system as potential dental materials. The microstructure of Ti–xGe alloys changes from single α‐Ti phase to α‐Ti + Ti5Ge3 precipitation phase with the increase of Ge content. Mechanical tests show that Ti–5Ge alloy has the best comprehensive mechanical properties. The corrosion behavior of Ti–xGe alloys in artificial saliva with different NaF and lactic acid addition at 37°C indicates that Ti–2Ge and Ti–5Ge alloys show better corrosion resistance to fluorine‐containing solution. The cytotoxicity test indicates that Ti–xGe alloy extracts show no obvious reduction of cell viability to L‐929 fibroblasts and MG‐63 osteosarcoma cells, similar to pure Ti which is generally acknowledged to be biocompatible. Considering all these results, Ti–2Ge and Ti–5Ge alloys possess the optimal comprehensive performance and might be used as potential dental materials. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012.
ISSN:1552-4973
1552-4981
DOI:10.1002/jbm.b.32793