Optical Coherence Tomography-Derived Anatomical Criteria for Functionally Significant Coronary Stenosis Assessed by Fractional Flow Reserve

Background: For the identification of functionally significant coronary artery disease, there have not been any dedicated optical coherence tomography (OCT) studies reported previously, although OCT can clearly detect coronary vessel lumina at higher resolution than intravascular ultrasound (IVUS)....

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Bibliographic Details
Published in:Circulation Journal 2012, Vol.76(9), pp.2218-2225
Main Authors: Shiono, Yasutsugu, Kitabata, Hironori, Kubo, Takashi, Masuno, Tomizou, Ohta, Shingo, Ozaki, Yuichi, Sougawa, Hiromichi, Orii, Makoto, Shimamura, Kunihiro, Ishibashi, Kohei, Komukai, Kenichi, Yamano, Takashi, Tanimoto, Takashi, Ino, Yasushi, Yamaguchi, Tomoyuki, Hirata, Kumiko, Mizukoshi, Masato, Imanishi, Toshio, Akasaka, Takashi
Format: Article
Language:English
Subjects:
Aged
Coronary Stenosis - pathology
Coronary Stenosis - physiopathology
Coronary Vessels - pathology
Coronary Vessels - physiopathology
Female
Fractional flow reserve
Fractional Flow Reserve, Myocardial
Humans
Hyperemia - pathology
Hyperemia - physiopathology
Intermediate coronary stenosis
Male
Middle Aged
Optical coherence tomography
Tomography, Optical Coherence
Ultrasonography, Interventional - methods
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Summary:Background: For the identification of functionally significant coronary artery disease, there have not been any dedicated optical coherence tomography (OCT) studies reported previously, although OCT can clearly detect coronary vessel lumina at higher resolution than intravascular ultrasound (IVUS). Methods and Results: OCT and fractional flow reserve (FFR) measurements were performed in 62 intermediate coronary lesions in 59 patients. FFR was calculated as the ratio of distal coronary pressure divided by proximal coronary pressure during maximal hyperemia. FFR
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.CJ-12-0195