Concentration of Thyroglobulin and Thyroglobulin-Specific Autoantibodies in Patients With Differentiated Thyroid Cancer After Treatment With Radioactive Iodine 131

Measurement of serum thyroglobulin (Tg) is primarily used as a tumor marker in the postoperative management of patients with differentiated thyroid cancer (DTC), while thyroglobulin autoantibodies (TgAbs) are elevated in some patients as well. Here, Savin et al evaluate the concentrations of Tg and...

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Bibliographic Details
Published in:Laboratory medicine 2011-01, Vol.42 (1), p.27-31
Main Authors: Vrndic, Olgica B., Savin, Svetlana B., Mijatovic, Ljiljana C., Djukic, Aleksandar A., Jeftic, Ilija D., Zivancevic Simonovic, Snezana T.
Format: Article
Language:English
Subjects:
Autoantibodies
Cancer
Clinical outcomes
Disease management
Iodine
Medical treatment
Metastases
Secretion
Thyroglobulin
thyroid cancer
Thyroid diseases
Thyroid-stimulating hormone
Tumor markers
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Summary:Measurement of serum thyroglobulin (Tg) is primarily used as a tumor marker in the postoperative management of patients with differentiated thyroid cancer (DTC), while thyroglobulin autoantibodies (TgAbs) are elevated in some patients as well. Here, Savin et al evaluate the concentrations of Tg and TgAbs in DTC patients 3 and 6 months after radiolodine therapy and to analyze whether the development and course of TgAbs is related to the clinical status of DTC patients or Tg levels before and after radioiodine therapy. H
ISSN:0007-5027
1943-7730
DOI:10.1309/LMNC7I58JNJMCPKW