Effects of Machine-Assisted Cycling on Exercise Capacity and Endothelial Function in Elderly Patients With Heart Failure

Background: Conventional exercise training (ET) for elderly patients with heart failure (HF) includes low-intensity stretching and gait training. The effects of 2 types of low-intensity ET - machine-assisted cycling and conventional ET - on exercise capacity and endothelial function of elderly patie...

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Bibliographic Details
Published in:Circulation Journal 2012, Vol.76(8), pp.1889-1894
Main Authors: Ozasa, Neiko, Morimoto, Takeshi, Bao, Bingyuan, Shioi, Tetsuo, Kimura, Takeshi
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Elderly
Endothelium
Endothelium, Vascular - physiopathology
Exercise
Female
Heart failure
Heart Failure - physiopathology
Heart Failure - therapy
Humans
Male
Resistance Training
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Summary:Background: Conventional exercise training (ET) for elderly patients with heart failure (HF) includes low-intensity stretching and gait training. The effects of 2 types of low-intensity ET - machine-assisted cycling and conventional ET - on exercise capacity and endothelial function of elderly patients with HF was investigated in the present study. Methods and Results: Twenty-seven elderly patients with HF (mean age: 79.5 years) were randomly assigned to either a machine-assisted cycling group or a conventional ET group. At baseline and after 2 weeks of ET, all patients were tested for 6-minute walk distance (6MWD) and digital reactive hyperemia-peripheral arterial tonometry (RH-PAT). After 2 weeks of ET, a significant increase in 6MWD was observed in both groups with no significant difference between the groups. RH-PAT index significantly increased in patients aged ≤80 (1.55±0.33 to 1.93±0.62, P=0.035) and a trend toward increase in RH-PAT index in the machine-assisted cycling group was observed (1.59±0.52 to 1.93±0.63, P=0.053), although no change was observed in the conventional ET group. In the multivariate model, patients’ age and machine-assisted cycling were associated with the increases in RH-PAT index (P
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.CJ-11-1113