Photoacoustic imaging using an adaptive interferometer with a photorefractive crystal

In this paper we report on remote three‐dimensional photoacoustic imaging without the need for a coupling agent or other aids (e.g. detector foils) by utilizing a two‐wave mixing interferometer (TWMI). In this technique the beams coming from sample and reference are brought to interfere in a Bi12SiO...

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Bibliographic Details
Published in:Journal of biophotonics 2012-07, Vol.5 (7), p.508-517
Main Authors: Hochreiner, Armin, Berer, Thomas, Grün, Hubert, Leitner, Michael, Burgholzer, Peter
Format: Article
Language:English
Subjects:
Adipose Tissue - blood supply
Algorithms
Animals
Blood Vessels - cytology
Crystallization
Forearm
Humans
Image Processing, Computer-Assisted
interferometer
Interferometry - instrumentation
Interferometry - methods
Light
Milk - chemistry
Molecular Imaging - instrumentation
Molecular Imaging - methods
Optical Phenomena
Phantoms, Imaging
photoacoustic imaging
Photoacoustic Techniques - instrumentation
Photoacoustic Techniques - methods
photorefractive crystal
Skin - cytology
Surface Properties
Swine
ultrasound detection
Water - chemistry
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Summary:In this paper we report on remote three‐dimensional photoacoustic imaging without the need for a coupling agent or other aids (e.g. detector foils) by utilizing a two‐wave mixing interferometer (TWMI). In this technique the beams coming from sample and reference are brought to interfere in a Bi12SiO20 photorefractive crystal (PRC). Such a setup allows the measurement of ultrasonic displacements on rough sample surfaces. After data acquisition the initial pressure distribution is reconstructed by a Fourier domain synthetic aperture focusing technique (FSAFT). We present three‐dimensional imaging of a hair ribbon phantom, on biological samples with embedded artificial blood vessels or pig bristles, and measurements on a human forearm in‐vivo. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
ISSN:1864-063X
1864-0648
DOI:10.1002/jbio.201100111