Diabetes and raised blood glucose as risk factors for future suicide: cohort study of 1 234 927 Korean men and women

BackgroundA diagnosis of diabetes has been shown to be a risk factor for suicide in selected studies. The link between blood glucose and future suicide has yet to be examined.AimTo examine if diabetes and blood glucose level are associated with a raised risk of suicide.MethodsThe Korean Cancer Preve...

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Bibliographic Details
Published in:	Journal of epidemiology and community health (1979) 2012-07, Vol.66 (7), p.650-652
Main Authors:	David Batty, G, Kivimaki, Mika, Park, Il Su, Jee, Sun Ha
Format:	Article
Language:	eng
Subjects:	Adult Aged Aged, 80 and over Biological and medical sciences Blood glucose Body mass index cancer CHD/coronorary heart Cohort Studies Diabetes Diabetes Mellitus, Type 2 Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Epidemiology Etiopathogenesis. Screening. Investigations. Target tissue resistance Fasting Female General aspects Glucose Humans Hyperglycemia Male Medical sciences Men Mental depression Middle Aged Miscellaneous Mortality Public health. Hygiene Public health. Hygiene-occupational medicine Republic of Korea - epidemiology Risk Factors Short reports Suicide Suicide - trends Type 1 diabetes mellitus Type 2 diabetes mellitus Womens health
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Summary:	BackgroundA diagnosis of diabetes has been shown to be a risk factor for suicide in selected studies. The link between blood glucose and future suicide has yet to be examined.AimTo examine if diabetes and blood glucose level are associated with a raised risk of suicide.MethodsThe Korean Cancer Prevention Study is a cohort of 1 329 525 individuals (482 618 women) aged 30–95 years at baseline. A fasting serum specimen was assayed for blood glucose, and diabetes status was categorised into five groups based on existing definitions. Study members were followed for mortality experience over 14 years.ResultsThere were 472 suicide deaths (389 in men and 83 in women) during the follow-up. In men, there was a ‘J’-shaped diabetes–suicide death relation. Thus, while the highest suicide rates were apparent in those with type 2 diabetes and there was an incremental fall in suicide risk with decreasing blood glucose level, an inflection was seen in the low-normal group. Similar results were apparent in women, although there was no raised risk in the lowest blood glucose group.ConclusionIn the present cohort, diabetes (both existing and study detected) but not raised blood glucose was a risk factor for completed suicide.
ISSN:	0143-005X 1470-2738