Persistence of hypercalciuria after successful surgical treatment for primary hyperparathyroidism

Primary hyperparathyroidism (PHPT) causes hypercalciuria and stone disease in a subset of patients. Hypercalciuria typically normalizes after surgery, although the risk of stone formation may persist up to 10 years. There are few reports in the literature that show persistent hypercalciuria despite...

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Bibliographic Details
Published in:International urology and nephrology 2012-06, Vol.44 (3), p.857-863
Main Authors: Spivacow, Francisco Rodolfo, Negri, Armando Luis, del Valle, Elisa Elena, Fradinger, Erich, Martinez, Carolina, Polonsky, Ana
Format: Article
Language:English
Subjects:
Aged
Calcium - blood
Calcium - urine
Creatinine - blood
Creatinine - urine
Female
Humans
Hypercalciuria - blood
Hypercalciuria - complications
Hypercalciuria - etiology
Hyperparathyroidism, Primary - complications
Hyperparathyroidism, Primary - surgery
Hyperparathyroidism, Primary - urine
Kidney Calculi - etiology
Kidney Calculi - urine
Male
Medicine
Medicine & Public Health
Middle Aged
Nephrology
Nephrology – Original Paper
Parathyroid Hormone - blood
Parathyroidectomy
Phosphorus - blood
Phosphorus - urine
Postoperative Period
Preoperative Period
Retrospective Studies
Urology
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Summary:Primary hyperparathyroidism (PHPT) causes hypercalciuria and stone disease in a subset of patients. Hypercalciuria typically normalizes after surgery, although the risk of stone formation may persist up to 10 years. There are few reports in the literature that show persistent hypercalciuria despite normalization of serum calcium after parathyroid surgery. We retrospectively analyzed 111 patients with PHPT from the osteoporosis, and stone clinics seen between 1999 and 2006. We selected only patients who had a complete metabolic profile that included 24-hour collections before and at least 3 months after parathyroidectomy. We excluded patients who had creatinine clearance
ISSN:0301-1623
1573-2584
DOI:10.1007/s11255-011-9953-6