Pheochromocytoma in Multiple Endocrine Neoplasia Type 2A: Positive 123I MIBG With Negative CT and Equivocal 131I MIBG Imaging

ABSTRACTAn I metaiodobenzylguanidine (MIBG) planar image showed abnormal uptake in the left adrenal gland and thyroid in a 24-year-old woman with multiple endocrine neoplasia type 2A. I MIBG showed abnormal uptake in the thyroid but not in the adrenal gland. Abdominal CT with 2-mm thin slices demons...

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Bibliographic Details
Published in:Clinical nuclear medicine 2012-06, Vol.37 (6), p.596-598
Main Authors: Ishii, Shirou, Shishido, Fumio, Miyajima, Masayuki, Sakuma, Kotaro, Kikuchi, Ken
Format: Article
Language:English
Subjects:
3-Iodobenzylguanidine
Adrenal Gland Neoplasms - complications
Adrenal Gland Neoplasms - diagnosis
Adrenal Gland Neoplasms - diagnostic imaging
Female
Humans
Multiple Endocrine Neoplasia - complications
Pheochromocytoma - complications
Pheochromocytoma - diagnosis
Pheochromocytoma - diagnostic imaging
Radionuclide Imaging
Tomography, X-Ray Computed
Young Adult
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Summary:ABSTRACTAn I metaiodobenzylguanidine (MIBG) planar image showed abnormal uptake in the left adrenal gland and thyroid in a 24-year-old woman with multiple endocrine neoplasia type 2A. I MIBG showed abnormal uptake in the thyroid but not in the adrenal gland. Abdominal CT with 2-mm thin slices demonstrated a normal adrenal gland. Postoperative pathologic findings were consistent with medullary carcinoma in both thyroid lobes and a small 1-mm pheochromocytoma in the left adrenal gland. I MIBG could clearly show the small pheochromocytoma, which was negative in thin-slice CT and equivocal in I MIBG.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0b013e31824c5f43