Correlative Interrelations between the Oxygen Consumption Rate, Body Temperature and Activities of the Key Antioxidant Enzymes of Liver of Mus musculus

Using one-, two-, and three-dimensional statistical methods, there were analyzed peculiarities of distribution and the degree of the correlative-regressional dependence between the parameters characterizing the oxygen consumption rate (V^sub O2^), body temperature (BT), activities of three key enzym...

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Bibliographic Details
Published in:Journal of evolutionary biochemistry and physiology 2004-01, Vol.40 (1), p.62-65
Main Authors: Muradian, Kh. K., Utko, N. A., Mozzhukhina, T. G., Pishel, I. N., Litoshenko, A. Ya, Bezrukov, V. V., Fraifeld, V. E.
Format: Article
Language:English
Subjects:
Oxygen
Statistical methods
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Summary:Using one-, two-, and three-dimensional statistical methods, there were analyzed peculiarities of distribution and the degree of the correlative-regressional dependence between the parameters characterizing the oxygen consumption rate (V^sub O2^), body temperature (BT), activities of three key enzymes of the antioxidant system - superoxide dismutase (SOD), catalase (CL), and glutathion peroxidase (GP) in 15 females of the laboratory population of Mus musculus. The performed studies have shown that the three-dimensional non-linear models better correspond to the actual data and clearly demonstrate specificity of the antioxidant enzymes, as regulatory targets. Changes of the SOD and CL activities depend mainly on V^sub O2^, whereas GP can be the target equally accessible for the regulatory factors of oxidative processes and thermoregulation.[PUBLICATION ABSTRACT]
ISSN:0022-0930
1608-3202
DOI:10.1023/B:JOEY.0000031006.56138.74