Photodynamic therapy for focal ablation of the prostate

Although in early stages of clinical development, photodynamic therapy (PDT) shows promise in delivering focal treatment of both primary and post-radiotherapy prostate cancer. This article will review the mechanism of action of PDT, previous research using PDT for treating prostate cancer including...

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Bibliographic Details
Published in:World journal of urology 2010-10, Vol.28 (5), p.571-576
Main Authors: Arumainayagam, Nimalan, Moore, C. M., Ahmed, Hashim U., Emberton, M.
Format: Article
Language:English
Subjects:
Dihematoporphyrin Ether - therapeutic use
Humans
Male
Medicine
Medicine & Public Health
Mesoporphyrins - therapeutic use
Metalloporphyrins - therapeutic use
Nephrology
Oncology
Photochemotherapy - adverse effects
Photosensitizing Agents - therapeutic use
Prostatic Neoplasms - drug therapy
Topic Paper
Treatment Outcome
Urology
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Summary:Although in early stages of clinical development, photodynamic therapy (PDT) shows promise in delivering focal treatment of both primary and post-radiotherapy prostate cancer. This article will review the mechanism of action of PDT, previous research using PDT for treating prostate cancer including the development of newer vascular-acting photosensitizers, and the potential advantages and disadvantages of PDT in delivering focal therapy.
ISSN:0724-4983
1433-8726
DOI:10.1007/s00345-010-0554-2