Cellulose‐enriched ascorbic acid for wound dressing application: Future medical textile

Abstract Wounds infected by resistant microbes have become a cost and health problem worldwide. In modern wound care, healing mechanisms require particular strategies, such as adding natural antioxidants and antimicrobials in a biocompatible biopolymer matrix mimicking extracellular tissue such as c...

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Bibliographic Details
Published in:Journal of applied polymer science 2024-10, Vol.141 (39)
Main Authors: Firmanda, Afrinal, Mahardika, Melbi, Fahma, Farah, Amelia, Devita, Pratama, Agus Wedi, Amalia, Nanda, Syafri, Edi, Achaby, Mounir El
Format: Article
Language:English
Subjects:
Acid resistance
Ascorbic acid
Biocompatibility
Biological effects
Biopolymers
Cellulose
Medical materials
Raw materials
Three dimensional printing
Wound healing
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Summary:Abstract Wounds infected by resistant microbes have become a cost and health problem worldwide. In modern wound care, healing mechanisms require particular strategies, such as adding natural antioxidants and antimicrobials in a biocompatible biopolymer matrix mimicking extracellular tissue such as cellulose. Here, ascorbic acid or Vitamin C is a promising bioactive as a topical drug loaded in a cellulose‐based composite matrix for skin tissue repair. Ascorbic acid, cellulose, or cellulose composites enriched with ascorbic acid have shown better biocompatibility and biological effects for accelerating wound healing, making them promising as sustainable medical textiles. Future challenges relate to the ideal engineered wound dressing design, raw material toxicity, and 3D printing technology.
ISSN:0021-8995
1097-4628
DOI:10.1002/app.56013