One Virus, Two Diseases: Evaluation of Clinical and Immunological Differences in Covid-19 and Multisystem Inflammatory Syndrome Cases

[LANGUAGE= "English"] Objectives: This study aims to uncover early detection markers through the immunological analysis of children diagnosed with multisystem inflammatory syndrome (MIS-C) and coronavirus disease-2019 (COVID-19).Methods: We retrospectively analyzed immunological data from...

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Bibliographic Details
Published in:Şişli Etfal Hastanesi tıp bülteni 2024-01, Vol.58 (1), p.82
Main Authors: Sefika Ilknur Kokcu Karadag, Erdeniz, Emine Hafize, Ozkan, Esra, Yildiran, Alisan
Format: Article
Language:Turkish
Subjects:
Anemia
Coronaviruses
COVID-19
Immunology
Lymphocytes
Polymerase chain reaction
Thrombocytopenia
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Summary:[LANGUAGE= "English"] Objectives: This study aims to uncover early detection markers through the immunological analysis of children diagnosed with multisystem inflammatory syndrome (MIS-C) and coronavirus disease-2019 (COVID-19).Methods: We retrospectively analyzed immunological data from thirty-three MIS-C patients and an equivalent number of patients under the age of 18 with a positive polymerase chain reaction (PCR) test for COVID-19. These individuals were admitted to Ondokuz Mayis University between November 2020 and February 2021. In total, the study group consisted of 66 patients and an additional 10 healthy controls.Results: Lymphopenia, thrombocytopenia, anemia, and neutrophilia, along with elevated levels of ferritin, D-dimer, and C-reactive protein, were more pronounced in MIS-C patients (p
ISSN:1302-7123
1308-5123
DOI:10.14744/SEMB.2023.23316