Management of Pet Allergies in Children in China

Purpose of the review With the increase in pet keeping among families in China, there has been a corresponding increase in the incidence of allergic diseases such as bronchial asthma and allergic rhinoconjunctivitis. Pet allergies pose important social and health problems, making their management in...

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Bibliographic Details
Published in:Current treatment options in allergy 2021-06, Vol.8 (2), p.111-119
Main Authors: Li, Ya-Ting, Jiang, Yu-Lin, Li, Hai-Feng, Zhu, Ling-Ping, Zhou, Jing-Wen, Dai, Zhen-Yuan, Yang, Li-Fen, Yang, Qin-Tai, Chen, Zhuang-Gui
Format: Article
Language:English
Subjects:
Allergens
Allergic diseases
Allergies
Allergology
Allergy Prevention (DY Wang
Asthma
Cats
Children
Cytokines
Dander
Diagnosis
Dogs
Family Medicine
General Practice
Hay fever
Hygiene
Hypersensitivity
Immunoglobulin E
Immunotherapy
Lymphocytes T
Medicine
Medicine & Public Health
Molecular weight
Pets
Quality of life
Rhinitis
Rhinoconjunctivitis
Risk factors
Section Editor
Skin
Skin tests
Topical Collection on Allergy Prevention
Urine
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Summary:Purpose of the review With the increase in pet keeping among families in China, there has been a corresponding increase in the incidence of allergic diseases such as bronchial asthma and allergic rhinoconjunctivitis. Pet allergies pose important social and health problems, making their management in children crucial. Recent findings There is an increasing trend of sensitization to cat and dog dander among Chinese children. The process underlying allergic sensitization is complex and is associated with an IgE-mediated type I hypersensitivity reaction that involves the upregulation of type 2 T-helper (Th2) cells, resulting in Th2 immunity. Compared with traditional serum-specific IgE (sIgE) and skin tests, molecular diagnosis may be better at predicting the progression of diseases. The association between pet keeping and allergic diseases in children remains controversial. Although the hygiene hypothesis is widely accepted in Chinese children, exposure to pets in early life remains a risk factor for allergies. Summary Pet avoidance and allergy immunotherapy (AIT) are recommended for children with pet allergies. However, pet avoidance is difficult to maintain, and AIT is not widely available in China. There is an imbalance between the increase in allergic diseases and the shortage of prevention and treatment options. We hope that advancements in medicine, diagnosis, and healthcare policies will help resolve this issue.
ISSN:2196-3053
2196-3053
DOI:10.1007/s40521-021-00279-x