Core–shell “loading-type” nanomaterials enabling glucometer readout for portable and sensitive detection of p-aminophenol in real samples

A one-target-many-trigger signal model sensing strategy is proposed for quickly, sensitive and on-site detection of the environmental pollutant p-aminophenol (PAP) by use of a commercial personal glucose meter (PGM) for signal readout with the core–shell “loading-type” nanomaterial MSNs@MnO 2 as amp...

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Bibliographic Details
Published in:Mikrochimica acta (1966) 2024-03, Vol.191 (3), p.127, Article 127
Main Authors: Li, Xiang-Ling, Zhao, Lei, Wang, Zi-Heng, Song, Tian-Shun, Guo, Ting, Xie, Jing Jing
Format: Article
Language:English
Subjects:
Aminophenol
Aminophenols
Amplification
Analytical Chemistry
Characterization and Evaluation of Materials
Chemistry
Chemistry and Materials Science
Glucose
Manganese Compounds
Manganese dioxide
Microengineering
Nanochemistry
Nanomaterials
Nanoparticles
Nanostructures
Nanotechnology
Onsite
Original Paper
Oxides
Pollutants
Redox reactions
Silicon Dioxide
Soil water
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Summary:A one-target-many-trigger signal model sensing strategy is proposed for quickly, sensitive and on-site detection of the environmental pollutant p-aminophenol (PAP) by use of a commercial personal glucose meter (PGM) for signal readout with the core–shell “loading-type” nanomaterial MSNs@MnO 2 as amplifiable nanoprobes. In this design, the mesoporous silica nanoparticles (MSNs) nanocontainer with entrapped signal molecule glucose is coated with redoxable manganese dioxide (MnO 2 ) nanosheets to form the amplifiable nanoprobes (Glu-MSNs@MnO 2 ). When encountered with PAP, the redox reaction between the MnO 2 and PAP can induce the degradation of the outer layer of MSNs@MnO 2 , liberating multiple copies of the loaded glucose to light up the PGM signal. Owing to the high loading capability of nanocarriers, a “one-to-many” relationship exists between the target and the signal molecule glucose, which can generate adequate signal outputs to achieve the requirement of on-site determination of environmental pollutants. Taking advantage of this amplification mode, the developed PAP assay owns a dynamic linear range of 10.0–400 μM with a detection limit of 2.78 μM and provides good practical application performance with above 96.7 ± 4.83% recovery in environmental water and soil samples. Therefore, the PGM-based amplifiable sensor for PAP proposed can accommodate these requirements of environment monitoring and has promising potential for evaluating pollutants in real environmental samples. Graphical Abstract
ISSN:0026-3672
1436-5073
DOI:10.1007/s00604-024-06204-8