Multifunctional Photosensitizers for PDT and Unique Fluorescent Sensors Based on the New Series of Cyanoaryl Porphyrazines with 4-(2-Propinyloxy)phenyl and 4-Benzyloxyphenyl Fragments in a Macrocycle Framing

New series of cyanoaryl porphyrazines with 4-(2-propinyloxy)phenyl and 4-benzyleoxyphenyl fragments in a macrocycle framing was reported. All the compounds reported on exhibit a good potential as the effective photosensitizer for photodynamic therapy (PDT). Moreover, they demonstrate unique combinat...

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Bibliographic Details
Published in:Russian journal of general chemistry 2023-12, Vol.93 (Suppl 3), p.S672-S687
Main Authors: Lermontova, S. A., Lyubova, T. S., Grigoryev, I. S., Ilichev, V. A., Plekhanov, V. I., Shilyagina, N. Yu, Balalaeva, I. V., Boyarskiy, V. P., Klapshina, L. G.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Fluorescence
Fragments
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Summary:New series of cyanoaryl porphyrazines with 4-(2-propinyloxy)phenyl and 4-benzyleoxyphenyl fragments in a macrocycle framing was reported. All the compounds reported on exhibit a good potential as the effective photosensitizer for photodynamic therapy (PDT). Moreover, they demonstrate unique combination of photodynamic activity and double sensory capacity toward environmental rigidity and polarity that is the promising platform for specifically personalized medicine.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363223160053