Syphilis-Related Nephropathy: A Rare Manifestation of a Re-emerging Disease

Syphilis is a curable sexually transmitted infection caused by the spirochete . Its clinical manifestations are variable as it has a remarkable aptitude to imitate a spectrum of clinical pictures. This phenomenon has bestowed upon it the epithet "the great imitator" within the medical lite...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-12, Vol.15 (12), p.e50105
Main Authors: Aal Hamad, Aya, Al Hadhrami, Zeyana, Al Lawati, Ali, Al Busaidi, Ibrahim, Mahmood, Saja
Format: Article
Language:English
Subjects:
Abdomen
Anemia
Antibodies
Antigens
Atrophy
Biopsy
Chlamydia
Creatinine
Diabetes
Edema
Emergency medical care
Hemoglobin
HIV
Human immunodeficiency virus
Infections
Kidney diseases
Males
Microscopy
Patients
Penicillin
Proteins
Serology
Stains & staining
Syphilis
Urine
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Summary:Syphilis is a curable sexually transmitted infection caused by the spirochete . Its clinical manifestations are variable as it has a remarkable aptitude to imitate a spectrum of clinical pictures. This phenomenon has bestowed upon it the epithet "the great imitator" within the medical literature. The escalating global prevalence of syphilis cases underscores the importance of shedding light on its rare manifestations. Syphilitic nephropathy is an uncommon manifestation of secondary syphilis. Here, we report two cases of syphilis-related nephropathy, the first presented as a nephrotic syndrome, and the second as a nephritic syndrome. Both cases had a favorable outcome after treatment of syphilis with benzathine penicillin G.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.50105