A randomized controlled comparative study of different fluid exchange modes in urgent-start peritoneal dialysis in patients with end-stage renal disease: automated peritoneal dialysis combined with manual fluid exchange vs. manual fluid exchange alone

During urgent-start peritoneal dialysis (USPD) in end-stage renal disease (ESRD) patients, both adequate dialysis and skill training for fluid exchange are essential. However, automated peritoneal dialysis (APD) alone or manual fluid exchange peritoneal dialysis (MPD) alone could meet the above dema...

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Bibliographic Details
Published in:Renal failure 2023-12, Vol.45 (1), p.2202756-2202756
Main Authors: Xia, Xiaoxiao, He, Xueqin, Pu, Li, Liu, Xia, Zhou, Xueli, Wu, Xiao Fang, Zang, Zhiyun, Li, Zi
Format: Article
Language:English
Subjects:
Automated peritoneal dialysis
Automation
Blood Urea Nitrogen
Carbon dioxide
Clinical Study
Creatinine
End-stage renal disease
Hemodialysis
Humans
Kidney diseases
Kidney Failure, Chronic - therapy
manual fluid exchange peritoneal dialysis
Peritoneal Dialysis
Peritoneum
Prospective Studies
Renal Dialysis
urgent-start peritoneal dialysis
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Summary:During urgent-start peritoneal dialysis (USPD) in end-stage renal disease (ESRD) patients, both adequate dialysis and skill training for fluid exchange are essential. However, automated peritoneal dialysis (APD) alone or manual fluid exchange peritoneal dialysis (MPD) alone could meet the above demands. Therefore, our study combined APD with MPD (A-MPD), and compared A-MPD with MPD, aiming to find the most appropriate treatment mode. This was a single-center, prospective, randomized controlled study. All eligible patients were randomized into the MPD and A-MPD groups. All patients underwent a five-day USPD treatment 48 h after catheter implantation, and they were followed up for six months after discharge. Overall, 74 patients were enrolled in this study. Among these, 14 and 60 patients quit due to complications during USPD and completed the study (A-MPD = 31, MPD = 29), respectively. Compared with MPD, the A-MPD treatment mode had a better effect on removing serum creatinine, blood urea nitrogen, and potassium and improving serum carbon dioxide combining power levels; it had less time expenditure on the fluid exchange by nurses (p 
ISSN:0886-022X
1525-6049
DOI:10.1080/0886022X.2023.2202756