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A Co‐Ni‐CM Heterogeneous Catalyst for the Direct Synthesis of Amides from the Oxidative Coupling of Aldehydes with N‐Substituted Formamides
Given the importance of amides in pharmaceutical and chemical industries, a Co−Ni composites (Co−Ni‐CM) heterogeneous catalytic system for the synthesis of amides from the oxidative coupling of aldehydes with N‐substituted formamides has been developed under mild conditions. The catalyst was prepare...
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Published in: | ChemCatChem 2023-09, Vol.15 (18), p.n/a |
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Main Authors: | , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Given the importance of amides in pharmaceutical and chemical industries, a Co−Ni composites (Co−Ni‐CM) heterogeneous catalytic system for the synthesis of amides from the oxidative coupling of aldehydes with N‐substituted formamides has been developed under mild conditions. The catalyst was prepared by pyrolysis under ambient atmosphere using Co‐BTC supported NiCl2 as a precursor. The catalytic system possesses good catalytic ability and good compatibility with functional groups. The surface morphology and internal element composition of the catalyst were characterized by powder X‐ray diffraction (XRD), BET adsorption, high resolution transmission electron microscope (HRTEM), scanning electron microscope (SEM), inductively coupled plasma emission spectroscopy (ICP‐OES) and X‐ray photoelectron spectroscopy (XPS). The results show that the interaction of Co−Ni is a key factor for the good catalytic activity of the catalyst. Then control experiments related to the mechanism of this transformation indicate a free radical process is involved in this transformation. More importantly, the catalyst has an excellent recycling performance and can be recycled seven times without obvious loss of catalytic activity.
Co−Ni‐CM catalyst with the high catalytic performance for the oxidative amidation of aldehydes and N‐substituted formamides has been synthesized. This protocol features a wide range of aldehydes and N‐substituted formamides providing various amides in moderate to excellent yields with a low catalyst dosage under mild conditions. |
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ISSN: | 1867-3880 1867-3899 |
DOI: | 10.1002/cctc.202300715 |