In Vitro Activity of Organochalcogen Compounds: IV. Synthesis and Cytotoxic Effect of 4-(1,2,3-Thiadiazol-4-yl)furans Against HeLa, Sk-mel-2, and B16 Tumor Cell Lines

A new series of 4-(1,2,3-thiadiazol-4-yl)furan derivatives was prepared. Their in vitro antitumor activity was studied against human cervical carcinoma (HeLa), human (Sk-mel-2) and murine (B16) melanoma cell lines.

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Bibliographic Details
Published in:Russian journal of general chemistry 2023-06, Vol.93 (6), p.1513-1522
Main Authors: Pevzner, L. M., Makhneva, E. A., Shmakov, S. V., Petrov, M. L., Stepakov, A. V., Boitsov, V. M.
Format: Article
Language:English
Subjects:
Anticancer properties
Cervical cancer
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Furans
Tumors
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Description
Summary:A new series of 4-(1,2,3-thiadiazol-4-yl)furan derivatives was prepared. Their in vitro antitumor activity was studied against human cervical carcinoma (HeLa), human (Sk-mel-2) and murine (B16) melanoma cell lines.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363223060245