16 RAM cannula versus Infant Flow Driver systems for post-extubation non-invasive ventilation support in extremely preterm infants - A retrospective cohort study

Abstract Background Non-invasive ventilation (NIV) delivered by RAM cannula is being used for post-extubation support of preterm infants in some centers for its potential benefits of ease of setup and less nasal trauma. Objectives To assess characteristics and clinical outcomes for infants extubated...

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Bibliographic Details
Published in:Paediatrics & child health 2022-10, Vol.27 (Supplement_3), p.e6-e7
Main Authors: Kumar, Manoj, Keil, Eric
Format: Article
Language:English
Subjects:
Cohort analysis
Conferences
Extubation
Medical research
Newborn babies
Premature babies
Ventilation
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Summary:Abstract Background Non-invasive ventilation (NIV) delivered by RAM cannula is being used for post-extubation support of preterm infants in some centers for its potential benefits of ease of setup and less nasal trauma. Objectives To assess characteristics and clinical outcomes for infants extubated to NIV support delivered via RAM cannula, as compared to those extubated to Vyaire Infant Flow Driver (IFD) systems. Design/Methods Retrospective cohort study. All infants born at 25 to 27 + 6 weeks of gestation during a 3-year period (2016-2018) and admitted to a regional Level-3 NICU, were eligible if: 1) they were ventilated for RDS within 48 hours of birth, and 2) extubated to NIV support using RAM cannula or IFD systems (using Viasys or FabianTM devices). Primary outcome was the failure of the primary mode of NIV support within the first 72 hours post-extubation (defined as need for reintubation or change of initial NIV mode to prevent reintubation). We adjusted for antenatal steroid use and delivery route. Data was stratified for gestational age (GA) =26 wks. Sensitivity analysis were performed on additional parameters, e.g., inborn status, duration of initial ventilation restricted to
ISSN:1205-7088
1918-1485
DOI:10.1093/pch/pxac100.015