Chitosan-Unripe banana peel powder (UBPP) as a candidate for antibacterial wound dressing

Wound infections have spread seriously worldwide, especially in Indonesia. Based on the Basic Health Survey conducted by the Indonesian Ministry of Health, shows that the prevalence of injuries tends to be high in Indonesia. Therefore, proper wound care is needed to prevent the wound from infection...

Full description

Saved in:
Bibliographic Details
Main Authors: Rahmawan, Andi Bagus, Widiyanti, Prihartini, Hikmawati, Dyah
Format: Conference Proceeding
Language:English
Subjects:
Chitosan
Cytotoxicity
Functional groups
Swelling
Tensile strength
Toxicity
Ultimate tensile strength
Wound healing
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Wound infections have spread seriously worldwide, especially in Indonesia. Based on the Basic Health Survey conducted by the Indonesian Ministry of Health, shows that the prevalence of injuries tends to be high in Indonesia. Therefore, proper wound care is needed to prevent the wound from infection or other unwanted things. Various studies have been conducted to optimize the wound healing process. It is expected that materials that meet the standards for wound dressings will be produced using natural materials such as chitosan and banana peel. The purpose of this study is to confirm the change of unripe banana peel powder (UBPP) in the chitosan/UBPP dressing film. The changes in the concentration used were 0, 9, 10, and 11% wt. Membrane results were characterized by FTIR, SEM, tensile strength, cytotoxicity, swelling, and antibacterial tests. Based on tests in the functional group of FTIR, at a concentration of 10% wt UBPP showed an interaction between banana peel powder and chitosan at a wavelength of 3174.83 cm−1. The results of the SEM form of the 10% wt chitosan/UBPP sample showed a good interfacial appearance. Based on the tensile strength test, it can be seen that the ultimate tensile strength (UTS) value increases with the addition of the concentration of unripe banana peel powder (UBPP) and it can be seen that the UTS value has met the tensile strength standard. Cytotoxicity studies have shownthat all four samples are non-toxic, with more than 60% of live cells in the four samples. The addition of unripe banana peel powder reduces the swelling properties of water from the wound dressing. Antibacterial test results Synergistic results were shown for the highest antibacterial activity at a concentration of UBPP 11% wt.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0118715