Development of Bacterial Cellulose Membranes Incorporated with Plant Extracts

A new generation of functional healing membranes has been researched to avoid infection and improve wound healing, combining wound moisture maintenance properties, exudate removal, antimicrobial activity, and the absence of side effects. Thus, this work aims to synthesize wound dressing membranes of...

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Bibliographic Details
Published in:Macromolecular symposia. 2022-12, Vol.406 (1), p.n/a
Main Authors: Neves, Eduarda Zeni, Kumineck Junior, Sandro Rogério, Katrucha, Graziéli Paulino, Silveira, Victória Fonseca, Silveira, Márcia Luciane Lange, Pezzin, Ana Paula Testa, Schneider, Andréa Lima dos Santos, Garcia, Michele Cristina Formolo, Apati, Giannini Pasiznick
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
Antimicrobial activity
bacterial cellulose
Cellulose
Exudation
Flavonoids
incorporation
Membranes
Moisture effects
Phenolic compounds
Plant extracts
Side effects
Synthesis
Thermal stability
Thermogravimetric analysis
wound dressing
Wound healing
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Summary:A new generation of functional healing membranes has been researched to avoid infection and improve wound healing, combining wound moisture maintenance properties, exudate removal, antimicrobial activity, and the absence of side effects. Thus, this work aims to synthesize wound dressing membranes of bacterial cellulose (BC) incorporated with different plant extracts with antimicrobial properties. The BC membranes are synthesized by the bacterium Komagataeibacter hansenii and are associated with the extracts through the ex situ incorporation technique. The barbatimão extract presents the most significant total phenolic content and antimicrobial activity of the extracts researched. The determination of tannins and flavonoids confirms the extracts’ incorporation into the samples’ structure. The thermogravimetric analysis of the membranes incorporated with the extracts shows a reduction in the thermal stability relative to BC. The results show a good final extract for developing healing membranes with antimicrobial properties.
ISSN:1022-1360
1521-3900
DOI:10.1002/masy.202200031