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Reliability of Machine Learning in Eliminating Data Redundancy of Radiomics and Reflecting Pathophysiology in COVID-19 Pneumonia: Impact of CT Reconstruction Kernels on Accuracy

Background: Radiomical data are redundant but they might serve as a tool for lung quantitative assessment reflecting disease severity and actual physiological status of COVID-19 patients. Objective: Test the effectiveness of machine learning in eliminating data redundancy of radiomics and reflecting...

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Published in:IEEE access 2022, Vol.10, p.120901-120921
Main Authors: Statsenko, Yauhen, Habuza, Tetiana, Talako, Tatsiana, Kurbatova, Tetiana, Simiyu, Gillian Lylian, Smetanina, Darya, Sido, Juana, Qandil, Dana Sharif, Meribout, Sarah, Gelovani, Juri G., Gorkom, Klaus Neidl-Van, Almansoori, Taleb M., Zahmi, Fatmah Al, Loney, Tom, Bedson, Anthony, Naidoo, Nerissa, Dehdashtian, Alireza, Ljubisavljevic, Milos, Koteesh, Jamal Al, Das, Karuna M.
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Language:English
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Summary:Background: Radiomical data are redundant but they might serve as a tool for lung quantitative assessment reflecting disease severity and actual physiological status of COVID-19 patients. Objective: Test the effectiveness of machine learning in eliminating data redundancy of radiomics and reflecting pathophysiologic changes in patients with COVID-19 pneumonia. Methods: We analyzed 605 cases admitted to Al Ain Hospital from 24 February to 1 July, 2020. They met the following inclusion criteria: age \geq 18 years; inpatient admission; PCR positive for SARS-CoV-2; lung CT available at PACS. We categorized cases into 4 classes: mild
ISSN:2169-3536
2169-3536
DOI:10.1109/ACCESS.2022.3211080