Synthesis and Biological Activity of Aminophosphabetaines with Long-chain Substitutes at the Nitrogen Atom

Aminophosphabetaines containing higher alkyl substituents at the nitrogen atom were synthesized by a three-stage procedure. The structure of the products was proved by IR and NMR spectroscopy, mass spectrometry, and X-ray diffraction analysis. All the synthesized compounds showed moderate antimicrob...

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Bibliographic Details
Published in:Russian journal of organic chemistry 2022-08, Vol.58 (8), p.1093-1098
Main Authors: Davletshin, R. R., Gayneev, A. M., Davletshina, N. V., Galkina, I. V., Ivshin, K. A., Shulaeva, M. P.
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
Biological activity
Chemistry
Chemistry and Materials Science
Infrared spectroscopy
Mass spectrometry
Nitrogen
NMR spectroscopy
Organic Chemistry
Synthesis
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Summary:Aminophosphabetaines containing higher alkyl substituents at the nitrogen atom were synthesized by a three-stage procedure. The structure of the products was proved by IR and NMR spectroscopy, mass spectrometry, and X-ray diffraction analysis. All the synthesized compounds showed moderate antimicrobial activity against B. cereus and S. aureus bacterial strains, as well as Candida albicans fungi.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428022080048