In-vivo Biocompatibility Evaluation of Different Self-Adhering Composite Resins on Wister Rats

This study aimed to compare the biocompatibility of two different self-adhering flowable resin composites (SAFCs). 54 polyethylene tubes filled with two different SAFCs [Group V: Vertise Flow (VF), Group F: Fusio Liquid Dentin (FLD), or Group C: empty (Control)] were implanted into the subcutaneous...

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Bibliographic Details
Published in:Journal of Photopolymer Science and Technology 2021, Vol.34(6), pp.579-585
Main Authors: Saygin, Ayşegül, Ünal, Murat, Koç, Tülay, İpek, İrem, Candan, Merve
Format: Article
Language:English
Subjects:
Biocompatibility
Composite materials
Necrosis
Polyethylenes
Self-adhering composite
Subcutaneous tissue
Thickness
Tubes
Wistar albino rat
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Summary:This study aimed to compare the biocompatibility of two different self-adhering flowable resin composites (SAFCs). 54 polyethylene tubes filled with two different SAFCs [Group V: Vertise Flow (VF), Group F: Fusio Liquid Dentin (FLD), or Group C: empty (Control)] were implanted into the subcutaneous tissue of 18 rats. After 7, 30, and 90 days of implantation, the rats were euthanatized (n=6). The implanted materials were removed with the surrounding tissue for histologic evaluation. The subjects were evaluated in terms of inflammation, fibrous capsule thickness, necrosis, macrophage, and giant cell presence. When the SAFC groups and Group C were compared on days 7, 30, and 90, inflammation, fibrous capsule thickness, and macrophage on the 7th day were statistically significant (p
ISSN:0914-9244
1349-6336
DOI:10.2494/photopolymer.34.579