Submolecular Ligand Size and Spacing for Cell Adhesion (Adv. Mater. 27/2022)

Cell Adhesion In article number 2110340, Ramasamy Paulmurugan, Young Keun Kim, Heemin Kang, and co‐workers report template‐mediated in situ tuning of nanoligand size and spacing. They demonstrate that submolecular ligand spacing and magnetic ligand anchoring facilitate adhesion‐structure assembly‐me...

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Published in:Advanced materials (Weinheim) 2022-07, Vol.34 (27), p.n/a
Main Authors: Kim, Yuri, Koo, Thomas Myeongseok, Thangam, Ramar, Kim, Myeong Soo, Jang, Woo Young, Kang, Nayeon, Min, Sunhong, Kim, Seong Yeol, Yang, Letao, Hong, Hyunsik, Jung, Hee Joon, Koh, Eui Kwan, Patel, Kapil D., Lee, Sungkyu, Fu, Hong En, Jeon, Yoo Sang, Park, Bum Chul, Kim, Soo Young, Park, Steve, Lee, Junmin, Gu, Luo, Kim, Dong‐Hyun, Kim, Tae‐Hyung, Lee, Ki‐Bum, Jeong, Woong Kyo, Paulmurugan, Ramasamy, Kim, Young Keun, Kang, Heemin
Format: Article
Language:English
Subjects:
Cell adhesion
ligand size
ligand spacing
Ligands
macrophage modulation
Macrophages
Materials science
nanoassemblies
submolecular ligands
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Summary:Cell Adhesion In article number 2110340, Ramasamy Paulmurugan, Young Keun Kim, Heemin Kang, and co‐workers report template‐mediated in situ tuning of nanoligand size and spacing. They demonstrate that submolecular ligand spacing and magnetic ligand anchoring facilitate adhesion‐structure assembly‐mediated pro‐healing polarization of host macrophages. Increasing the ligand spacing significantly suppresses macrophage adhesion whereas increasing both ligand size and spacing slightly inhibits it.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.202270203