Samarium(ii)-electrocatalyzed chemoselective reductive alkoxylation of phthalimides

The unprecedented samarium electrocatalyzed reductive alkoxylation of phthalimides in a single step is presented. Under mild conditions, using electrogenerated Sm(ii) with TMSCl (trimethyl chlorosilane), N-substituted 3-alkoxyl isoindolin-1-ones are isolated in good to excellent yields with high fun...

Full description

Saved in:
Bibliographic Details
Published in:Organic chemistry frontiers an international journal of organic chemistry 2022-03, Vol.9 (5), p.1308-1314
Main Authors: Yu-Feng, Zhang, Mellah, Mohamed
Format: Article
Language:English
Subjects:
Electrocatalysis
Functional groups
Organic chemistry
Phthalimides
Samarium
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The unprecedented samarium electrocatalyzed reductive alkoxylation of phthalimides in a single step is presented. Under mild conditions, using electrogenerated Sm(ii) with TMSCl (trimethyl chlorosilane), N-substituted 3-alkoxyl isoindolin-1-ones are isolated in good to excellent yields with high functional group tolerance.
ISSN:2052-4110
2052-4110
DOI:10.1039/d1qo01760h