Synthesis of New 1-Hydroxy-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one Derivatives

Aldol addition of acyclic and cyclic ketones to 4,4,6-trimethyl-4 H -pyrrolo[3,2,1- ij ]quinoline-1,2-diones afforded the corresponding 1-substituted 1-hydroxy-4,4,6-trimethyl-4 H -pyrrolo[3,2,1- ij ]quinolin-2(1 H )-ones. The short-time reduction of 4,4,6-trimethyl-4 H -pyrrolo[3,2,1- ij ]quinoline...

Full description

Saved in:
Bibliographic Details
Published in:Russian journal of organic chemistry 2021-10, Vol.57 (10), p.1592-1599
Main Authors: Novichikhina, N. P., Shestakov, A. S., Skoptsova, A. A., Ashrafova, Z. E., Stolpovskaya, N. V., Kosheleva, E. A., Shatalov, G. V., Ledenyova, I. V., Shikhaliev, Kh. S.
Format: Article
Language:English
Subjects:
Aldehydes
Chemistry
Chemistry and Materials Science
Diketones
Ketones
Organic Chemistry
Quinoline
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aldol addition of acyclic and cyclic ketones to 4,4,6-trimethyl-4 H -pyrrolo[3,2,1- ij ]quinoline-1,2-diones afforded the corresponding 1-substituted 1-hydroxy-4,4,6-trimethyl-4 H -pyrrolo[3,2,1- ij ]quinolin-2(1 H )-ones. The short-time reduction of 4,4,6-trimethyl-4 H -pyrrolo[3,2,1- ij ]quinoline-1,2-diones with sodium tetra­hydridoborate gave 1-hydroxy-4,4,6-trimethyl-4 H -pyrrolo[3,2,1- ij ]quinolin-2(1 H )-ones.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428021100043