The Role of Colloidal Gold in the Photodynamic Effect

To increase the effectiveness of photodynamic therapy, new photosensitizers are searched for, as well as suitable sources, illuminators, and means of delivery are developed. Also, attempts are made to additionally use various external influences and various nanoparticles for the delivery of photosen...

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Bibliographic Details
Published in:Journal of Russian laser research 2021-11, Vol.42 (6), p.667-670
Main Authors: Gulidov, M. D., Zhorina, L. V., Zadorozhny, N. A.
Format: Article
Language:English
Subjects:
Absorption spectra
Cell death
Colloids
Electron microscopes
Gold
Illuminators
Lasers
Microwaves
Nanoparticles
Optical Devices
Optics
Photodynamic therapy
Photonics
Physics
Physics and Astronomy
RF and Optical Engineering
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Summary:To increase the effectiveness of photodynamic therapy, new photosensitizers are searched for, as well as suitable sources, illuminators, and means of delivery are developed. Also, attempts are made to additionally use various external influences and various nanoparticles for the delivery of photosensitizers. This includes the use of colloidal gold for photodynamic effects combined with a photosensitizer. In this paper, we make an attempt to determine whether colloidal gold itself causes cell death when they are irradiated within its absorption band. We find that colloidal gold does not cause photodynamic effects in the absence of a photosensitizer.
ISSN:1071-2836
1573-8760
DOI:10.1007/s10946-021-10007-0