Statistical Optimization of Medium Compoments to Improve the Antibiotic Activity of Streptomyces sp. 19G-317

Statistical Optimization of Medium Compoments to Improve the Antibiotic Activity of Streptomyces sp. 19G-317

In this paper, fermentation parameters for the production of antibiotics by Streptomyces sp.19G-317 to enhance the antibiotic activity were optimized using a sequential optimization strategy, including the single factor, Plackett-Burman (PB) design, steepest ascent experiment and response surface me...

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Bibliographic Details
Published in:African journal of agricultural research 2011-09, Vol.6 (19), p.4424-4431
Main Authors: Zhang, Xing, Han, Lirong, Feng, Juntao, Zhang, Wugang
Format: Article
Language:eng
Subjects:
Antibiotics
Fermentation
Science and Technology
Scientific research
Online Access:Get full text
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Summary:In this paper, fermentation parameters for the production of antibiotics by Streptomyces sp.19G-317 to enhance the antibiotic activity were optimized using a sequential optimization strategy, including the single factor, Plackett-Burman (PB) design, steepest ascent experiment and response surface methodology (RSM). Research methodology is described and key findings are reported.
ISSN:1991-637X
1991-637X