Loading…
Pharmaceutical biotechnological potential of filamentous fungi isolated from textile industry
The need for more effective drugs for the treatment of infectious diseases as well as for general applications including wound healing and burn surgery, has guided efforts for the discovery of new compounds of medical interest. Microorganisms found in textile industrial waste have the ability to pro...
Saved in:
| Published in: | Archives of microbiology 2021-09, Vol.203 (7), p.3933-3944 |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c352t-afbdc744a1e162451fead4949ef35d63d7e4ce25fd76735b644da03a21f278d03 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c352t-afbdc744a1e162451fead4949ef35d63d7e4ce25fd76735b644da03a21f278d03 |
| container_end_page | 3944 |
| container_issue | 7 |
| container_start_page | 3933 |
| container_title | Archives of microbiology |
| container_volume | 203 |
| creator | Bernal, Suzan Prado Fernandes Gritti, Micaela Andrea dos Santos, Viviane Piccin Ottoni, Júlia Ronzella de Oliveira, Valéria Maia Peichoto, Maria Elisa Passarini, Michel Rodrigo Zambrano |
| description | The need for more effective drugs for the treatment of infectious diseases as well as for general applications including wound healing and burn surgery, has guided efforts for the discovery of new compounds of medical interest. Microorganisms found in textile industrial waste have the ability to produce a variety of enzymes and/or secondary metabolites including molecules of pharmaceutical interest. The present work investigated the biotechnological potential of filamentous fungi isolated from textile industry wastewater for the production of collagenase and antimicrobial metabolites. From 28 isolates assayed,
Sarocladium
sp. ITF33 showed specific collagenolytic activity with values of 7.62 and 9.04 U mg
−1
for the intracellular and extracellular fractions, respectively. The isolate
Penicillium
sp. ITF28 showed the best antimicrobial activity, reaching MIC ranging from 1.0 to 0.0625 mg mL
−1
against five pathogenic bacteria. Molecular analyzes suggest that the isolate
Sarocladium
sp. ITF 33 can be considered a species not yet described. The results of the present work encourage studies of characterization and purification of the enzymes and secondary metabolites produced by the isolates found aiming future applications in the medical and pharmaceutical fields. |
| doi_str_mv | 10.1007/s00203-021-02379-3 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2560484937</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2560484937</sourcerecordid><originalsourceid>FETCH-LOGICAL-c352t-afbdc744a1e162451fead4949ef35d63d7e4ce25fd76735b644da03a21f278d03</originalsourceid><addsrcrecordid>eNp9kEtLAzEUhYMoWKt_wNWA69Gb3MxkZinFFxR0oeBGQjpJ2pTppCYZsP_e2AruXFzug3POhY-QSwrXFEDcRAAGWAKjuVC0JR6RCeXIShDs_ZhMAIGVTYt4Ss5iXANQ1jTNhHy8rFTYqM6MyXWqLxbOJ9OtBt_75f6wzfuQXJ68Lazr1SavfoyFHYelK1z0vUpGFzb4TZHMV3K9Kdygx5jC7pycWNVHc_Hbp-Tt_u519ljOnx-eZrfzssOKpVLZhe4E54oaWjNeUWuU5i1vjcVK16iF4Z1hldWiFlgtas61AlSMWiYaDTglV4fcbfCfo4lJrv0YhvxSsqoG3vAWRVaxg6oLPsZgrNwGt1FhJynIH4zygFFmjHKPUWI24cEUs3hYmvAX_Y_rGzHHd54</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2560484937</pqid></control><display><type>article</type><title>Pharmaceutical biotechnological potential of filamentous fungi isolated from textile industry</title><source>Springer Nature</source><creator>Bernal, Suzan Prado Fernandes ; Gritti, Micaela Andrea ; dos Santos, Viviane Piccin ; Ottoni, Júlia Ronzella ; de Oliveira, Valéria Maia ; Peichoto, Maria Elisa ; Passarini, Michel Rodrigo Zambrano</creator><creatorcontrib>Bernal, Suzan Prado Fernandes ; Gritti, Micaela Andrea ; dos Santos, Viviane Piccin ; Ottoni, Júlia Ronzella ; de Oliveira, Valéria Maia ; Peichoto, Maria Elisa ; Passarini, Michel Rodrigo Zambrano</creatorcontrib><description>The need for more effective drugs for the treatment of infectious diseases as well as for general applications including wound healing and burn surgery, has guided efforts for the discovery of new compounds of medical interest. Microorganisms found in textile industrial waste have the ability to produce a variety of enzymes and/or secondary metabolites including molecules of pharmaceutical interest. The present work investigated the biotechnological potential of filamentous fungi isolated from textile industry wastewater for the production of collagenase and antimicrobial metabolites. From 28 isolates assayed,
Sarocladium
sp. ITF33 showed specific collagenolytic activity with values of 7.62 and 9.04 U mg
−1
for the intracellular and extracellular fractions, respectively. The isolate
Penicillium
sp. ITF28 showed the best antimicrobial activity, reaching MIC ranging from 1.0 to 0.0625 mg mL
−1
against five pathogenic bacteria. Molecular analyzes suggest that the isolate
Sarocladium
sp. ITF 33 can be considered a species not yet described. The results of the present work encourage studies of characterization and purification of the enzymes and secondary metabolites produced by the isolates found aiming future applications in the medical and pharmaceutical fields.</description><identifier>ISSN: 0302-8933</identifier><identifier>EISSN: 1432-072X</identifier><identifier>DOI: 10.1007/s00203-021-02379-3</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Antiinfectives and antibacterials ; Antimicrobial activity ; Antimicrobial agents ; Biochemistry ; Biomedical and Life Sciences ; Biotechnology ; Cell Biology ; Collagen ; Collagenase ; Ecology ; Enzymes ; Fungi ; Industrial wastes ; Infectious diseases ; Life Sciences ; Metabolites ; Microbial Ecology ; Microbiology ; Microorganisms ; Minimum inhibitory concentration ; Original Paper ; Pharmaceuticals ; Secondary metabolites ; Textile industry ; Textile industry wastewaters ; Wastewater ; Wound healing</subject><ispartof>Archives of microbiology, 2021-09, Vol.203 (7), p.3933-3944</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c352t-afbdc744a1e162451fead4949ef35d63d7e4ce25fd76735b644da03a21f278d03</citedby><cites>FETCH-LOGICAL-c352t-afbdc744a1e162451fead4949ef35d63d7e4ce25fd76735b644da03a21f278d03</cites><orcidid>0000-0002-8614-1896</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,783,787,27938,27939</link.rule.ids></links><search><creatorcontrib>Bernal, Suzan Prado Fernandes</creatorcontrib><creatorcontrib>Gritti, Micaela Andrea</creatorcontrib><creatorcontrib>dos Santos, Viviane Piccin</creatorcontrib><creatorcontrib>Ottoni, Júlia Ronzella</creatorcontrib><creatorcontrib>de Oliveira, Valéria Maia</creatorcontrib><creatorcontrib>Peichoto, Maria Elisa</creatorcontrib><creatorcontrib>Passarini, Michel Rodrigo Zambrano</creatorcontrib><title>Pharmaceutical biotechnological potential of filamentous fungi isolated from textile industry</title><title>Archives of microbiology</title><addtitle>Arch Microbiol</addtitle><description>The need for more effective drugs for the treatment of infectious diseases as well as for general applications including wound healing and burn surgery, has guided efforts for the discovery of new compounds of medical interest. Microorganisms found in textile industrial waste have the ability to produce a variety of enzymes and/or secondary metabolites including molecules of pharmaceutical interest. The present work investigated the biotechnological potential of filamentous fungi isolated from textile industry wastewater for the production of collagenase and antimicrobial metabolites. From 28 isolates assayed,
Sarocladium
sp. ITF33 showed specific collagenolytic activity with values of 7.62 and 9.04 U mg
−1
for the intracellular and extracellular fractions, respectively. The isolate
Penicillium
sp. ITF28 showed the best antimicrobial activity, reaching MIC ranging from 1.0 to 0.0625 mg mL
−1
against five pathogenic bacteria. Molecular analyzes suggest that the isolate
Sarocladium
sp. ITF 33 can be considered a species not yet described. The results of the present work encourage studies of characterization and purification of the enzymes and secondary metabolites produced by the isolates found aiming future applications in the medical and pharmaceutical fields.</description><subject>Antiinfectives and antibacterials</subject><subject>Antimicrobial activity</subject><subject>Antimicrobial agents</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Cell Biology</subject><subject>Collagen</subject><subject>Collagenase</subject><subject>Ecology</subject><subject>Enzymes</subject><subject>Fungi</subject><subject>Industrial wastes</subject><subject>Infectious diseases</subject><subject>Life Sciences</subject><subject>Metabolites</subject><subject>Microbial Ecology</subject><subject>Microbiology</subject><subject>Microorganisms</subject><subject>Minimum inhibitory concentration</subject><subject>Original Paper</subject><subject>Pharmaceuticals</subject><subject>Secondary metabolites</subject><subject>Textile industry</subject><subject>Textile industry wastewaters</subject><subject>Wastewater</subject><subject>Wound healing</subject><issn>0302-8933</issn><issn>1432-072X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kEtLAzEUhYMoWKt_wNWA69Gb3MxkZinFFxR0oeBGQjpJ2pTppCYZsP_e2AruXFzug3POhY-QSwrXFEDcRAAGWAKjuVC0JR6RCeXIShDs_ZhMAIGVTYt4Ss5iXANQ1jTNhHy8rFTYqM6MyXWqLxbOJ9OtBt_75f6wzfuQXJ68Lazr1SavfoyFHYelK1z0vUpGFzb4TZHMV3K9Kdygx5jC7pycWNVHc_Hbp-Tt_u519ljOnx-eZrfzssOKpVLZhe4E54oaWjNeUWuU5i1vjcVK16iF4Z1hldWiFlgtas61AlSMWiYaDTglV4fcbfCfo4lJrv0YhvxSsqoG3vAWRVaxg6oLPsZgrNwGt1FhJynIH4zygFFmjHKPUWI24cEUs3hYmvAX_Y_rGzHHd54</recordid><startdate>20210901</startdate><enddate>20210901</enddate><creator>Bernal, Suzan Prado Fernandes</creator><creator>Gritti, Micaela Andrea</creator><creator>dos Santos, Viviane Piccin</creator><creator>Ottoni, Júlia Ronzella</creator><creator>de Oliveira, Valéria Maia</creator><creator>Peichoto, Maria Elisa</creator><creator>Passarini, Michel Rodrigo Zambrano</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>RC3</scope><orcidid>https://orcid.org/0000-0002-8614-1896</orcidid></search><sort><creationdate>20210901</creationdate><title>Pharmaceutical biotechnological potential of filamentous fungi isolated from textile industry</title><author>Bernal, Suzan Prado Fernandes ; Gritti, Micaela Andrea ; dos Santos, Viviane Piccin ; Ottoni, Júlia Ronzella ; de Oliveira, Valéria Maia ; Peichoto, Maria Elisa ; Passarini, Michel Rodrigo Zambrano</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c352t-afbdc744a1e162451fead4949ef35d63d7e4ce25fd76735b644da03a21f278d03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Antiinfectives and antibacterials</topic><topic>Antimicrobial activity</topic><topic>Antimicrobial agents</topic><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Biotechnology</topic><topic>Cell Biology</topic><topic>Collagen</topic><topic>Collagenase</topic><topic>Ecology</topic><topic>Enzymes</topic><topic>Fungi</topic><topic>Industrial wastes</topic><topic>Infectious diseases</topic><topic>Life Sciences</topic><topic>Metabolites</topic><topic>Microbial Ecology</topic><topic>Microbiology</topic><topic>Microorganisms</topic><topic>Minimum inhibitory concentration</topic><topic>Original Paper</topic><topic>Pharmaceuticals</topic><topic>Secondary metabolites</topic><topic>Textile industry</topic><topic>Textile industry wastewaters</topic><topic>Wastewater</topic><topic>Wound healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bernal, Suzan Prado Fernandes</creatorcontrib><creatorcontrib>Gritti, Micaela Andrea</creatorcontrib><creatorcontrib>dos Santos, Viviane Piccin</creatorcontrib><creatorcontrib>Ottoni, Júlia Ronzella</creatorcontrib><creatorcontrib>de Oliveira, Valéria Maia</creatorcontrib><creatorcontrib>Peichoto, Maria Elisa</creatorcontrib><creatorcontrib>Passarini, Michel Rodrigo Zambrano</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Genetics Abstracts</collection><jtitle>Archives of microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bernal, Suzan Prado Fernandes</au><au>Gritti, Micaela Andrea</au><au>dos Santos, Viviane Piccin</au><au>Ottoni, Júlia Ronzella</au><au>de Oliveira, Valéria Maia</au><au>Peichoto, Maria Elisa</au><au>Passarini, Michel Rodrigo Zambrano</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pharmaceutical biotechnological potential of filamentous fungi isolated from textile industry</atitle><jtitle>Archives of microbiology</jtitle><stitle>Arch Microbiol</stitle><date>2021-09-01</date><risdate>2021</risdate><volume>203</volume><issue>7</issue><spage>3933</spage><epage>3944</epage><pages>3933-3944</pages><issn>0302-8933</issn><eissn>1432-072X</eissn><abstract>The need for more effective drugs for the treatment of infectious diseases as well as for general applications including wound healing and burn surgery, has guided efforts for the discovery of new compounds of medical interest. Microorganisms found in textile industrial waste have the ability to produce a variety of enzymes and/or secondary metabolites including molecules of pharmaceutical interest. The present work investigated the biotechnological potential of filamentous fungi isolated from textile industry wastewater for the production of collagenase and antimicrobial metabolites. From 28 isolates assayed,
Sarocladium
sp. ITF33 showed specific collagenolytic activity with values of 7.62 and 9.04 U mg
−1
for the intracellular and extracellular fractions, respectively. The isolate
Penicillium
sp. ITF28 showed the best antimicrobial activity, reaching MIC ranging from 1.0 to 0.0625 mg mL
−1
against five pathogenic bacteria. Molecular analyzes suggest that the isolate
Sarocladium
sp. ITF 33 can be considered a species not yet described. The results of the present work encourage studies of characterization and purification of the enzymes and secondary metabolites produced by the isolates found aiming future applications in the medical and pharmaceutical fields.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><doi>10.1007/s00203-021-02379-3</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-8614-1896</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0302-8933 |
| ispartof | Archives of microbiology, 2021-09, Vol.203 (7), p.3933-3944 |
| issn | 0302-8933 1432-072X |
| language | eng |
| recordid | cdi_proquest_journals_2560484937 |
| source | Springer Nature |
| subjects | Antiinfectives and antibacterials Antimicrobial activity Antimicrobial agents Biochemistry Biomedical and Life Sciences Biotechnology Cell Biology Collagen Collagenase Ecology Enzymes Fungi Industrial wastes Infectious diseases Life Sciences Metabolites Microbial Ecology Microbiology Microorganisms Minimum inhibitory concentration Original Paper Pharmaceuticals Secondary metabolites Textile industry Textile industry wastewaters Wastewater Wound healing |
| title | Pharmaceutical biotechnological potential of filamentous fungi isolated from textile industry |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-11-01T09%3A41%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pharmaceutical%20biotechnological%20potential%20of%20filamentous%20fungi%20isolated%20from%20textile%20industry&rft.jtitle=Archives%20of%20microbiology&rft.au=Bernal,%20Suzan%20Prado%20Fernandes&rft.date=2021-09-01&rft.volume=203&rft.issue=7&rft.spage=3933&rft.epage=3944&rft.pages=3933-3944&rft.issn=0302-8933&rft.eissn=1432-072X&rft_id=info:doi/10.1007/s00203-021-02379-3&rft_dat=%3Cproquest_cross%3E2560484937%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c352t-afbdc744a1e162451fead4949ef35d63d7e4ce25fd76735b644da03a21f278d03%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2560484937&rft_id=info:pmid/&rfr_iscdi=true |