1065 EFFECT OF BIRTHPLACE ON CARDIOMETABOLIC PROFILE AMONG BLACKS WITH METABOLIC SYNDROME AND SLEEP APNEA RISK

Abstract Introduction: Metabolic syndrome poses an increased burden of disease, warranting heightened public health attention. This study assessed effects of birthplace on cardiometabolic profile among blacks with metabolic syndrome and sleep apnea risk, while exploring potential gender-based effect...

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Bibliographic Details
Published in:Sleep (New York, N.Y.) N.Y.), 2017-04, Vol.40 (suppl_1), p.A396-A396
Main Authors: Rogers, A, Ravenell, J, Seixas, A, Newsome, V, Ogedegbe, C, Williams, N, Zizi, F, Casimir, G, Jean-Louis, G
Format: Article
Language:English
Subjects:
Blood pressure
Cholesterol
Diabetes
Gender
Glucose
Metabolic syndrome
Sleep apnea
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Summary:Abstract Introduction: Metabolic syndrome poses an increased burden of disease, warranting heightened public health attention. This study assessed effects of birthplace on cardiometabolic profile among blacks with metabolic syndrome and sleep apnea risk, while exploring potential gender-based effects. Methods: This analysis is based on data from 610 black patients (mean age= 63 ± 11 years female=65%) with evidence of metabolic syndrome and were at risk for sleep apnea using the ARES. Participants from four community-based clinics in Brooklyn, NY provided sociodemographic, medical, and clinical data. Clinical data included body mass index (BMI), blood pressure (BP), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), and fasting plasma glucose (FPG) or hemoglobin (HbA1c) for those who had a diagnosis of diabetes. General Linear Model (GLM) was used to assess effects of birthplace and gender on cardiometabolic parameters, adjusting for age effects. Results: Of the sample, 61.6 % were foreign-born blacks (FBB) and 38.4 % were US-born blacks (USB). FBB had significantly lower BMI compared with USB (32.76 ± 0.35 vs. 35.41 ± 0.44, F=22.57), but had significantly higher systolic blood pressure (136.70 ± 0.77 vs. 132.83 ± 0.98; F=9.60) and fasting glucose levels than did USB (146.46 ± 3.37 vs. 135.02 ± 4.27; F=4.40). Men had higher diastolic BP (76.67 ± 0.65 vs. 75.05 ± 0.45; F=4.20), glucose (146.53 ± 4.48 vs. 134.95 ± 3.07; F=4.55) and triglyceride levels (148.10 ± 4.51 vs. 130.60 ± 3.09; F=10.25) compared with women, but women had higher LDL-cholesterol (109.24 ± 1.49 vs. 98.49 ± 2.18; F=16.60) and HDL-cholesterol levels (50.71 ± 0.66 vs. 42.77 ± 0.97; F=46.01) than did men. Conclusion: FBB have lower levels of obesity, similar rates of hypertension, dyslipidemia, stroke history, but higher rates of diabetes, history of heart disease, and systolic BP compared with USB. Findings may have implications for addressing effects of birthplace and gender on cardiovascular disease outcomes. Support (If Any): NIH/NINDS U54NS081765 NIMHD R01MD007716 NHLBI R25HL105444
ISSN:0161-8105
1550-9109
DOI:10.1093/sleepj/zsx050.1064