Antibacterial activity of marine molluscs

To study the antibacterial activity of marine gastropods with different solvent extracts against human pathogenic bacteria. Different solvent extracts of Conus amadis Conus betulinus, Lambis lambis, Tonna dolium, Trochus radiatus, Hemifusus cochlidium were screened for their activity against Gram-po...

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Bibliographic Details
Published in:Journal of pharmaceutical and biological sciences 2015-11, Vol.3 (6), p.250
Main Authors: Selvaraju Meenakshi, Shanmugam Umayaparvathi, Ravichandran Saravanan, Thangavel Balasubramanian
Format: Article
Language:English
Subjects:
Antibacterial activity
Bacteria
Cholera
Conus
Gastropoda
Methanol
Minimum inhibitory concentration
Mollusca
Solvents
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Summary:To study the antibacterial activity of marine gastropods with different solvent extracts against human pathogenic bacteria. Different solvent extracts of Conus amadis Conus betulinus, Lambis lambis, Tonna dolium, Trochus radiatus, Hemifusus cochlidium were screened for their activity against Gram-positive (Streptococcus pneumonia, Micrococcus luteus, Enterococcus faecalis) and gram-negative (Vibrio cholera, Shigella flexneri) bacteria using standard disc diffusion method and its minimum inhibitory concentration. The study revealed that the methanol extract of the tissues inhibited the growth of the tested pathogenic bacterial strains than the methanol: choloroform extracts, this showed that methanol is suitable for extracting active compounds from mollusks. Of the six gastropods tested, minimum concentrations (25g/ml) of methanol extracts of the C. betulinus, T. dolium and H. cochlidium were effective in controlling the growth of the human pathogens. These above observed results showed the marine gastropod extracts were may use as additional antibacterial compounds to inhibit the growth of harmful human bacteria.
ISSN:2320-1924