Efficient one-pot three-component synthesis of 2H-indazole [2,1-b]phthalazine-1,6,11(13H)-triones at room temperature

Tetrabutylammonium bromide (TBAB) and cesium carbonate (Cs2O3) catalyzed, one-pot three-component synthesis of 2H-indazole[2,1b]phthalazine-1,6,11(13H)-triones was developed at room temperature in ethanol. Both electron donating and withdrawing groups are compatible under the optimized reaction para...

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Bibliographic Details
Published in:Organic communications 2020-10, Vol.13 (4), p.194-201
Main Authors: Pisal, Parshuram M., Kamble, Vinod T., Varala, Ravi, Gujarathi, Pradip B.
Format: Article
Language:English
Subjects:
Cesium
Chemical synthesis
Ethanol
Room temperature
Tetrabutylammonium bromide
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Summary:Tetrabutylammonium bromide (TBAB) and cesium carbonate (Cs2O3) catalyzed, one-pot three-component synthesis of 2H-indazole[2,1b]phthalazine-1,6,11(13H)-triones was developed at room temperature in ethanol. Both electron donating and withdrawing groups are compatible under the optimized reaction parameters.
ISSN:1307-6175
1307-6175
DOI:10.25135/acg.oc.85.20.08.1768