Gastrointestinal Perforation After Treatment With Tocilizumab

Factors significantly associated with this increased risk were age, medical history of diverticulitis, and use of high doses of steroids. 2 The last factor is especially important, as high-dose steroids are also used in patients with severe SARS-CoV-2 disease. 3 Diagnosis and treatment of gastrointe...

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Bibliographic Details
Published in:The American surgeon 2020-06, Vol.86 (6), p.565-566
Main Authors: Rojo, Mikel, Cano-Valderrama, Oscar, Picazo, Sara, Saez, Carlos, Gómez, Lorena, Sánchez, Cristina, Sanz-Ortega, Gonzalo, Torres, Antonio J
Format: Article
Language:English
Subjects:
Abdomen
Colon
Coronaviruses
COVID-19
Diagnosis
Drug dosages
Health services
Immunosuppressive agents
Mechanical ventilation
Medical diagnosis
Medical treatment
Monoclonal antibodies
Mortality
Ostomy
Pandemics
Patients
Peritonitis
Pneumonia
Rheumatoid arthritis
Sepsis
Severe acute respiratory syndrome coronavirus 2
Steroid hormones
Steroids
Surgery
Ventilation
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Summary:Factors significantly associated with this increased risk were age, medical history of diverticulitis, and use of high doses of steroids. 2 The last factor is especially important, as high-dose steroids are also used in patients with severe SARS-CoV-2 disease. 3 Diagnosis and treatment of gastrointestinal perforation is a challenge in these patients. First of all, diagnosis is difficult because patients are usually under mechanical ventilation and sepsis is common. [...]early diagnosis and treatment of this complication are essential.
ISSN:0003-1348
1555-9823
DOI:10.1177/0003134820926481