Assessment of risk scores in Covid‐19

Objective To analyse the accuracy of commonly used risk scores (PSI and CURB‐65) in predicting mortality and need for ICU admission in Covid‐19. Material and methods Prospective study of patients diagnosed with Covid‐19 pneumonia. Patients were followed until home discharge or death. PSI, CURB‐65, S...

Full description

Saved in:
Bibliographic Details
Published in:International Journal of Clinical Practice 2021-12, Vol.75 (12), p.e13705-n/a
Main Authors: García Clemente, Marta María, Herrero Huertas, Julia, Fernández Fernández, Alejandro, De La Escosura Muñoz, Covadonga, Enríquez Rodríguez, Ana Isabel, Pérez Martínez, Liliana, Gómez Mañas, Santiago, Iscar Urrutia, Marta, López González, Francisco Julián, Madrid Carbajal, Claudia Janeth, Bedate Díaz, Pedro, Arias Guillén, Miguel, Bailón Cuadrado, Cristina, Hermida Valverde, Tamara
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Community-Acquired Infections
COVID-19
Humans
Intensive Care Units
Lymphocytes
Male
Middle Aged
Mortality
Multivariate analysis
Pneumonia
Prognosis
Prospective Studies
Retrospective Studies
Risk Assessment
Risk Factors
SARS-CoV-2
Severity of Illness Index
Citations: Items that this one cites
Items that cite this one
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective To analyse the accuracy of commonly used risk scores (PSI and CURB‐65) in predicting mortality and need for ICU admission in Covid‐19. Material and methods Prospective study of patients diagnosed with Covid‐19 pneumonia. Patients were followed until home discharge or death. PSI, CURB‐65, SMART‐COP and MuLBSTA severity scores were assessed on admission. Risk scores were related to mortality and ICU admission. Results About 249 patients, 143 males (57.4%) were included. The mean age was 65.6 + 16.1 years. Factors associates with mortality in the multivariate analysis were age > 80 years (OR: 13.9; 95% CI 3.8‐51.1) (P = .000), lymphocytes  500 pg/mL (OR: 10.1; 95% CI 1.1‐63.1) (P = .039). In predicting mortality, the PSI score: AUC 0.874 (95% CI 0.808‐0.939) and the CURB‐65 score: AUC 0.852 (95% CI 0.794‐0.909) were the ones that obtained the best results. In the need for ICU admission, the SMART‐COP score: AUC 0.749 (95% CI 0.695‐0.820) and the MuLBSTA score: AUC 0.777 (95% CI 0.713‐0.840) were the ones that obtained better results, with significant differences with PSI and CURB‐65. The scores with the lowest value for ICU admission prediction were PSI with AUC of 0.620 (95% CI 0.549‐0.690) and CURB‐65 with AUC of 0.604 (95% CI 0.528‐0.680). Conclusions Prognosis scores routinely used for CAP (PSI and CURB‐65) were good predictors for mortality in patients with Covid‐19 CAP but not for need of hospitalisation or ICU admission. In the evaluation of Covid‐19 pneumonia, we need scores that allow to decide the appropriate level of care.
ISSN:1368-5031
1742-1241
DOI:10.1111/ijcp.13705